Benign Thyroid Nodules / Benign Goiter. What Subjective Problems Are Improved With an Operation and Can This be Predicted Preoperatively?

NCT ID: NCT05526261

Last Updated: 2022-09-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-30

Study Completion Date

2024-05-30

Brief Summary

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Nodules in the thyroid gland are common. Patients discover these lumps either because of their visible size increase or because of local discomforts such as difficulty swallowing, difficulty breathing or voice changes. The thyroid gland is in close connection with the esophagus, trachea and the vocal nerve. Thus, a lump in the thyroid gland can cause pressure symptoms from these organs. In the event of such complaints, patients are referred for investigation. If it turns out that the patient has a lump in the thyroid gland ("goiter"), further investigation is carried out with an ultrasound examination and sampling with a needle from the lump (puncture).

At present, most thyroid nodules are examined cytologically, ie the thyroid nodules are punctured with a thin needle and the cells that are obtained are analyzed by a cytologist. The material is graded according to Bethesda classification. Higher grading is associated with a higher risk that the tuber is malignant. Lower grading is associated with a lower probability that the tuber can be malignant. If these patients are operated on, it is usually with the hope that their local ailments improve.

We want to investigate which patients who have a lump in the thyroid gland and experience pressure problems experience an improvement after a thyroid operation.

Detailed Description

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Conditions

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Thyroid Nodule

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Hemithyroidectoy

Hemithyroidectomy it is a surgical procedure where half of the thyroid gland is operated.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with a thyroid nodule who have local problems and where surgery (hemithyroidectomy) is planned
* 18 years or older
* Bethesda I-IV

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Linkoeping University

OTHER_GOV

Sponsor Role lead

Responsible Party

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Ervin Beka

General Surgeon MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Oliver Gimm, Professor

Role: STUDY_DIRECTOR

Professor Oliver Gimm

Locations

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Linköpings University

Linköping, Östergötland County, Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Ervin Beka

Role: CONTACT

0738430968

Facility Contacts

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Ervin Beka

Role: primary

0738430968

Other Identifiers

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2020-00022

Identifier Type: -

Identifier Source: org_study_id

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