Changes in Esophageal Motility and Swallowing Symptoms After Thyroid Surgery

NCT ID: NCT03100357

Last Updated: 2017-04-04

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 39 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-10-31
• Study Completion Date: 2018-09-30

Brief Summary

The pronounced effect of goiter on the esophagus needs further exploration, as the mechanisms by which goiter leads to swallowing difficulties are unknown. By investigating esophageal motility using high resolution esophageal manometry before and after thyroidectomy we seek to examine the impact of the goiter mass on the esophagus and swallowing with six months follow-up.

Conditions

Esophageal Motility Disorders

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

Thyroidectomy

Thyroid surgery for benign nodular goiter

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients with symptomatic benign nodular goiter referred for thyroidectomy

Exclusion Criteria

• Previous surgery to the neck;
• Suspicion of thyroid cancer
• Age below 20 years or above 80 years
• Neuromuscular disease.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Southern Denmark

OTHER

Sponsor Role: lead

Responsible Party

Jesper Roed Sorensen

MD PhD fellow

Responsibility Role: PRINCIPAL_INVESTIGATOR

References

Sorensen JR, Markoew S, Dossing H, Hegedus L, Bonnema SJ, Godballe C. Changes in Swallowing Symptoms and Esophageal Motility After Thyroid Surgery: A Prospective Cohort Study. World J Surg. 2018 Apr;42(4):998-1004. doi: 10.1007/s00268-017-4247-5.

Reference Type: DERIVED

PMID: 29043407 (View on PubMed)

Other Identifiers

SOLOIST4

Identifier Type: -

Identifier Source: org_study_id