Effectiveness of an Online Self-management Intervention for Type 2 Diabetes Mellitus

NCT ID: NCT05525117

Last Updated: 2024-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-04

Study Completion Date

2024-12-15

Brief Summary

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This trial was designed to evaluate the effectiveness of the dialogue-based online intervention covivio, which was designed to improve diabetes self-management in patients with type 2 diabetes.

The study aims to test the hypothesis that covivio has a greater positive impact on glycemic control than treatment as usual. Patients with type 2 diabetes mellitus will be randomized and allocated to either an intervention group, receiving covivio in addition to treatment as usual, or a control group, which receives only treatment as usual. The primary endpoint is the HbA1c value six month after baseline.

Detailed Description

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The aim of this clinical trial is to investigate the effectiveness of the self-guided digital therapeutic covivio in 268 patients with type 2 diabetes mellitus (T2DM). Patients will be randomized and allocated in a 1:1 ratio to either an intervention group, in which they will receive access to covivio in addition to treatment as usual (TAU, n = 134), or to a control group, in which they will receive only TAU (n = 134).

The primary endpoint of this trial will be the between-groups difference of the HbA1c in the intervention and control group at six months adjusted for the baseline HbA1c. In order to show the course of change over time, two timepoints for assessment of effects are planned at four (T1) and six months (T2) after the baseline assessment (T0). The primary endpoint will be the HbA1c at six months post-allocation. Secondary endpoints will be depression, diabetes self-management (DSM), BMI, and quality of life. Figure 1 (section 6.1) summarizes the design of the clinical trial.

Conditions

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Type 2 Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

randomized controlled trial with two arms: (i) online intervention in addition to treatment-as-usual versus (ii) treatment-as-usual
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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online intervention in addition to treatment-as-usual

online intervention: covivio in addition to treatment as usual

Group Type EXPERIMENTAL

covivio (additional to treatment as usual)

Intervention Type BEHAVIORAL

Covivio is a dialogue-based online psychological intervention for patients with type 2 diabetes. This intervention includes elements that address disease literacy, physical activity and exercise, dieting and nutritional principles, coping with depression, etc. Content is adapted to users needs using interactive dialogues, illustrations and audio files. Participants may also continue with their usual treatment.

treatment-as-usual

Other: treatment as usual

Group Type OTHER

treatment as usual

Intervention Type OTHER

Participants may continue with any treatment that they require (treatment as usual)

Interventions

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covivio (additional to treatment as usual)

Covivio is a dialogue-based online psychological intervention for patients with type 2 diabetes. This intervention includes elements that address disease literacy, physical activity and exercise, dieting and nutritional principles, coping with depression, etc. Content is adapted to users needs using interactive dialogues, illustrations and audio files. Participants may also continue with their usual treatment.

Intervention Type BEHAVIORAL

treatment as usual

Participants may continue with any treatment that they require (treatment as usual)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* diagnosis of T2DM (submission of a medical certificate attesting to the presence of at least one of the following ICD-10-GM diagnoses of T2DM: E11.20, E11.30, E11.40, E11.50, E11.60, E11.72, E11.74, E11.80, E11.90)
* HbA1c value ≥ 7.0% (53 mmol/mol)
* BMI ≥ 23 kg/m2
* Consent to participate
* Sufficient knowledge of the German language

Exclusion Criteria

* diagnosis of type 1 diabetes mellitus (T1DM)
* change in medication, frequency of use or dosage (planned within 4 weeks before T0 or during the study period)
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Gaia AG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gitta Jacob, PD PhD

Role: PRINCIPAL_INVESTIGATOR

Gaia AG

Locations

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GAIA

Hamburg, , Germany

Site Status

Countries

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Germany

Other Identifiers

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covivio trial 2022

Identifier Type: -

Identifier Source: org_study_id

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