Identifying Biomarkers for Chronic Pain After Breast Cancer Treatment.
NCT ID: NCT05507034
Last Updated: 2023-12-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
150 participants
OBSERVATIONAL
2022-10-04
2025-06-30
Brief Summary
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evaluation of the pain. In daily clinical practice, however, guidelines for a comprehensive diagnosis of pain in cancer patients and survivors are lacking. Further research in this topic is crucial for an efficient, preventive as well as curative, approach of pain after breast cancer. Besides the high prevalence and the important impact of pain in this population, the breast cancer population is also an ideal population to study chronic pain and its natural time course in different stages, since most patients start pain-free, but almost half of them end up
with chronic pain. Therefore, this study aims to map biomarkers (both predictive, prognostic and diagnostic) for chronic pain after breast cancer treatment. We will study possible biopsychosocial biomarkers in
relation to (chronic) pain and monitor their temporal changes from the moment of diagnosis until 1 year after surgery. The potential biomarkers are situated within the medical imaging of the brain, measurements of pain sensitivity and psychological variables.
Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Breast cancer
Breast cancer patients following over time during cancer treatment
Biomarkers
Each intervention is performed at 4 timepoints namely: before surgery, i.e. baseline (T0), 1-3 weeks post-surgery (T1), 3 months post-surgery (T2) and 1 year post-surgery (T4)
Interventions
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Biomarkers
Each intervention is performed at 4 timepoints namely: before surgery, i.e. baseline (T0), 1-3 weeks post-surgery (T1), 3 months post-surgery (T2) and 1 year post-surgery (T4)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Pain at enrollment \<3/10 on average during the past week
* First cancer diagnosis
Exclusion Criteria
* major pre-existing neurological disorders
* No recurrent cancer or metastasis
* No previous surgery in area
25 Years
65 Years
FEMALE
No
Sponsors
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University Hospital, Antwerp
OTHER
Fund for Scientific Research, Flanders, Belgium
OTHER
Universiteit Antwerpen
OTHER
Responsible Party
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Prof. dr. Mira Meeús
Prof. Dr.
Principal Investigators
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Mira Meeus, Prof.
Role: PRINCIPAL_INVESTIGATOR
Universiteit Antwerpen
An De Groef, Prof.
Role: STUDY_CHAIR
Universiteit Antwerpen
Locations
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University Hospital Antwerpen
Wilrijk, Antwerpen, Belgium
Countries
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Central Contacts
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Facility Contacts
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Amber De Groote, Drs.
Role: primary
Related Links
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Other Identifiers
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1780
Identifier Type: -
Identifier Source: org_study_id