Functional MRI Evaluation in Pyeloureteral Junction Syndrome in Children

NCT ID: NCT05498532

Last Updated: 2022-08-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

270 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2022-12-30

Brief Summary

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Pyelo-ureteral junction syndrome is the most common urological abnormality in children.

Functional MRI has been evaluated several times, and had shown good correlation with scintigraphy, but tends to over estimate results. Moreover, those studies included a small number of cases. Its sensitivity to detect crossing polar vessel is limited.

We aimed to evaluate, in patients between 0 and 1 year old, the correlation between MRI and scintigraphy differential renal function.

Our secondary objectives are : evaluation of MRI performances to detect polar vessel ; comparison of surgery times depending of MRI only realisation or MRI and scintigraphy realisation.

Detailed Description

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Conditions

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Stricture of Pelviureteric Juncture

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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PUJS patients

Patients between 0 and 17 years old treated or followed for pyelo-ureteral junction syndrome.

Functional MRI

Intervention Type DIAGNOSTIC_TEST

Anatomical MRI : T2 fiesta, SSFE, HASTE ; 3D T2 ; T1 FAT SAT ; LAVA Functional MRI : T1 FAT SAT with gadolinium

Interventions

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Functional MRI

Anatomical MRI : T2 fiesta, SSFE, HASTE ; 3D T2 ; T1 FAT SAT ; LAVA Functional MRI : T1 FAT SAT with gadolinium

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Renal Scintigraphy

Eligibility Criteria

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Inclusion Criteria

* children between 0 and 17 years old
* followed for pyelo-ureteral junction syndrome

Exclusion Criteria

* none
Minimum Eligible Age

1 Day

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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Charles Mazeaud

Praticien hospitalier universitaire

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Charles Mazeaud

Role: PRINCIPAL_INVESTIGATOR

CHRU Nancy

Locations

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CHRU Nancy

Vandœuvre-lès-Nancy, Lorraine, France

Site Status

Countries

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France

Central Contacts

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Charles Mazeaud

Role: CONTACT

03 83 85 85 85

Other Identifiers

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2022PI108

Identifier Type: -

Identifier Source: org_study_id

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