Abdominal Ultrasonography in Urinary Tract Infection - When and Why?
NCT ID: NCT03270540
Last Updated: 2018-11-26
Study Results
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Basic Information
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COMPLETED
65 participants
OBSERVATIONAL
2017-03-13
2018-11-18
Brief Summary
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Abdominal ultrasonography (USG) is the first line imaging modality in evaluating children with UTI. Abnormalities suggesting CAKUT found on USG are an indication for further, more invasive tests. The timing of USG in UTI depends on the clinical situation. It always should be performed urgently when serious acute complications of UTI are suspected. However, appropriate timing of USG in children responding well to therapy, is a matter of debate. According to animal studies, E. coli produces toxin which dilates the urinary tract. This may result in misleading picture on USG in acute phase of infection. Guidelines on UTI management in children differ in respect to recommended USG timing.
The purpose of the study is to investigate how UTI does affect USG results in children and when its effect subsides.
Methods 150 children up to 3 years of age, with the first episode of UTI, will be included in our study. Three USG examinations will be performed by single radiologist in every child:
1. in the first day of treatment,
2. two weeks after treatment initiation,
3. four weeks after treatment initiation. Age, gender, etiologic factor, C-reactive protein concentration and white blood cells count will be included in statistical analysis.
The study is aimed to help clinicians interpret USG findings during UTI and make reasonable plans for further imaging diagnostics in children with UTI.
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* known congenital abnormality of the kidney and the urinary tract (CAKUT)
3 Years
ALL
No
Sponsors
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Medical University of Warsaw
OTHER
Responsible Party
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Magdalena Okarska-Napierała
MD
Locations
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Medical University of Warsaw Children's Hospital
Warsaw, , Poland
Countries
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Related Links
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National Institute for Health and Care Excellence. Urinary tract infections in children and young people 2013 July
European Association of Urology; European Society for Pediatric Urology Urinary tract infections in children: (EAU/ESPU) guidelines.
Canadian Paediatric Society, Urinary tract infection in infants and children: Diagnosis and management
Other Identifiers
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WarsawMU2W9
Identifier Type: -
Identifier Source: org_study_id
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