Primary Obstructive Megaureter Management in Eastern Interregional Area

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-02

Study Completion Date

2022-03-31

Brief Summary

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Congenital obstructive megaureter is a urinary malformation affecting the ureterovesical junction and causing obstruction to the flow of urine. It is the second most common cause of hydronephrosis. This malformation affects four times more boys than girls and is bilateral in 25% of cases. It is also associated with contralateral renal dysplasia in 15% of cases. The obstruction is linked to aperistalsis and hypertrophy of the circular muscle bundles and increased collagen 1 level. This malformation is accessible to antenatal screening from the second trimester. It falls within the scope of CAKUT and requires regular monitoring. Indeed, this uropathy can cause repeated pyelonephritis, kidney scarring and affected kidney function.

Detailed Description

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Conditions

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Congenital Obstructive Megaureter

Keywords

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Congenital obstructive megaureter Urinary malformation Ureterovesical junction Hydronephrosis Renal dysplasia

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Minor patient (from 1 to 17 years old)
* Patient treated between January 2010 and December 2017 in one of the participating centers for an obstructive congenital mega-ureter
* Subject (and/or his parental authority) not having expressed, after information, his opposition to the reuse of his data for the purposes of this research

Exclusion Criteria

* Subject (and/or his parental authority) having expressed, after information, his opposition to the reuse of his data for the purposes of this research

Minimum Eligible Age

1 Year

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Locations

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Service de Chirurgie pédiatrique - CHU de Strasbourg - France

Strasbourg, , France

Site Status

Countries

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France

Other Identifiers

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7978

Identifier Type: -

Identifier Source: org_study_id