Is Sheep Ghee Cardioprotective?

NCT ID: NCT05492279

Last Updated: 2022-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-01

Study Completion Date

2022-07-01

Brief Summary

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Normal volunteers were randomly received Sheep ghee or sunflower oil, and before and after the study lipid profile and HS-CRP were measured.

Detailed Description

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During outpatient clinic visits, potentially eligible individuals were screened for enrollment according to the inclusion and exclusion criteria.

Patients were randomly allocated into the treatment and control groups via the blocked randomization method.

The control group received a normal diet for eight weeks with 10 g of sunflower oil. In the treatment group, sunflower oil was replaced with 10 g of sheep ghee.

50 patients in each group were enrollment. Patients' information, including demographic data and the serum levels of fasting blood sugar (FBS), LDL, HDL, triglyceride (TG), and hs-CRP, were recorded in datasheets twice: once before treatment with sheep ghee and once eight weeks later.

Conditions

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Cholesterol; Metabolic Disorder Inflammation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

clinical trial randomized
Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
random allocation, open label

Study Groups

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intervention

10 gr Sheep ghee

Group Type EXPERIMENTAL

sheep ghee

Intervention Type DIETARY_SUPPLEMENT

natural sheep ghee, given to patient in a commercial box and intervention group 10 gr per day from sheep ghee

control group

10 gr sunflower oil

Group Type ACTIVE_COMPARATOR

sunflower oil

Intervention Type DIETARY_SUPPLEMENT

natural sunflower oil, given to patients in a commercial box and patient use 10 gr of it

Interventions

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sheep ghee

natural sheep ghee, given to patient in a commercial box and intervention group 10 gr per day from sheep ghee

Intervention Type DIETARY_SUPPLEMENT

sunflower oil

natural sunflower oil, given to patients in a commercial box and patient use 10 gr of it

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* healthy adults, seeking outpatient visit at professor kojuri cardiology clinic

Exclusion Criteria

* any history of ischemic heart disease (IHD),
* coronary artery bypass grafting (CABG)
* percutaneous intervention (PCI)
* stroke
* peripheral vascular diseases
* use of anti-hyperlipidemic agents
* unwillingness to participate.
* Need of tight hyperlipidemia control.
Minimum Eligible Age

20 Years

Maximum Eligible Age

76 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Shiraz University of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Javad Kojuri

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Javad Kojuri

Shiraz, Fars, Iran

Site Status

Countries

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Iran

Other Identifiers

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98-01-01-22054

Identifier Type: -

Identifier Source: org_study_id

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