Home-based Exercise Training for Lung Cancer Patients Awaiting Surgery

NCT ID: NCT05473052

Last Updated: 2022-07-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 15 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-02-01
• Study Completion Date: 2022-07-01

Brief Summary

Surgical resection is the only curative treatment in patients diagnosed with lung cancer, the most mortal type of malignancy globally. However, following lung cancer resection, patients experience a substantial deterioration in health-related quality of life and have an increased risk of developing pulmonary complications.

Although current clinical guidelines strongly recommend preoperative exercise training to improve clinical outcomes after lung cancer surgery, inaccessibility to facility-based exercise programs is a major barrier to routine participation, with patients indicating a strong preference to exercise in a home-based environment.

The primary purpose of the present study was to evaluate the feasibility of a home-based exercise program (HBEP) in lung cancer patients awaiting surgical treatment. The secondary purposes were to evaluate the safety of the HBEP and to explore exercise effects on patients' HRQOL and physical performance, either pre-and post-surgery.

Conditions

Lung Neoplasm

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: NONE

Study Groups

Preoperative home-based exercise training

Patients received usual care plus a preoperative home-based exercise program consisting of aerobic and resistance exercise. In addition, a physical therapist carried out weekly telephone supervision with all participants

Group Type: EXPERIMENTAL

Preoperative home-based exercise training

Intervention Type: BEHAVIORAL

1) Home-based aerobic and resistance exercise training (preoperative period)

Dose of aerobic exercise:

1. Type: Walking

2. Frequency: 3 sessions per week

3. Duration: 30 minutes

4. Intensity: Rate of perceived exertion on Borg Category Ratio-10 (3-5)

5. Progression: Increase the walking duration in 10 minutes (after week 2)

Dose of resistance exercise:

1. Type: Six exercises for upper and lower limbs using bodyweight and free-wights of 1-2kg

2. Frequency: 2 sessions per week

3. Duration: 2 sets x 15 repetitions

4. Rest in-between sets: 45 seconds

5. Intensity:Rate of perceived exertion on Borg Category Ratio-10 (3-5)

6. Progression: Increase the number of sets (3 sets of 15 repetitions after week

2) Weekly telephone supervision: A physical therapist carried out weekly telephone calls with all participants to monitor adverse events, give positive reinforcement and recommend strategies to overcome barriers that arise during the exercise program.

Interventions

Preoperative home-based exercise training

1) Home-based aerobic and resistance exercise training (preoperative period)

Dose of aerobic exercise:

1. Type: Walking

2. Frequency: 3 sessions per week

3. Duration: 30 minutes

4. Intensity: Rate of perceived exertion on Borg Category Ratio-10 (3-5)

5. Progression: Increase the walking duration in 10 minutes (after week 2)

Dose of resistance exercise:

1. Type: Six exercises for upper and lower limbs using bodyweight and free-wights of 1-2kg

2. Frequency: 2 sessions per week

3. Duration: 2 sets x 15 repetitions

4. Rest in-between sets: 45 seconds

5. Intensity:Rate of perceived exertion on Borg Category Ratio-10 (3-5)

6. Progression: Increase the number of sets (3 sets of 15 repetitions after week

2) Weekly telephone supervision: A physical therapist carried out weekly telephone calls with all participants to monitor adverse events, give positive reinforcement and recommend strategies to overcome barriers that arise during the exercise program.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Scheduled for surgical treatment of suspected or confirmed lung cancer (clinical stage IIIA or less)
• Waiting time for surgery of at least two weeks from baseline assessment
• Medical clearance to exercise.
• Signed informed consent prior to initiation of study-related procedures.

Exclusion Criteria

• Metastatic cancer
• Presence of physical or mental disabilities that contraindicated exercise training or physical testing
• Unable to communicate in Portuguese or English
• Performing combined aerobic plus resistance training over the past month (self-reported ≥2 days a week, ≥30 minutes each session).

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Instituto Politécnico de Leiria

OTHER

Sponsor Role: lead

Responsible Party

Pedro Machado

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Portuguese Oncology Institute of Coimbra

Coimbra, , Portugal

Countries

Portugal

Other Identifiers

HomeFittosurgery

Identifier Type: -

Identifier Source: org_study_id