Lung Resection and Pulmonary Rehabilitation

NCT ID: NCT04722393

Last Updated: 2021-01-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 66 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-10-01
• Study Completion Date: 2019-12-01

Brief Summary

Lung cancer is the most common cancer in the world and surgical resection remains the gold standard curative treatment in early stage non-small cell lung cancer. However, surgery itself is the direct cause of pulmonary function impairment, which dramatically reduces patients tolerance to exercise and their quality of life. Pulmonary rehabilitation (PR) complements surgical treatment and improves patients' exercise and functional capacity, decreases dyspnea, improves health status.

Our aim is to examine the effectiveness of PR applied after lung resection in patients with lung cancer, 2- To determine whether the respiratory exercise training given to patients who could not participate in the PR program is effective.

Detailed Description

Pulmonary rehabilitation (PR) is an evidence-based, interdisciplinary, comprehensive exercise program that targets patients with symptomatic chronic respiratory disease. PR integrates exercise and training interventions into a personalized treatment program. PR has become an important component of the general treatment strategy in patients with high-risk surgical diseases such as lung resection. It helps patients return to normal not only physically, but also emotionally and mentally. In patients with lung cancer, preoperative PR increases exercise capacity, decreases post-operative morbidity and mortality. Although it is reported that the PR program applied in the post-operative period increases physical performance and improves the quality of life, referral of patients in need of the PR unit is less than 25%. There is a need to increase the awareness of both pulmonologists and thoracic surgeons about the benefits of the PR program, which is a non-pharmacological and effective intervention.

The investigators have had two objectives in this study. 1- To examine the effectiveness of PR applied after lung resection in patients with lung cancer, 2- To determine whether the respiratory exercise training given to patients who could not participate in the PR program is effective.

An 8-week comprehensive outpatient PR program will applied to half of 66 patients with non-small cell lung cancer who underwent lung resection, and the other half received respiratory exercise training. After the intervention, the results of both groups will compare.

Conditions

Pulmonary Rehabilitation; Lung Cancer

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Pulmonary Rehabilitation Group

An 8-week comprehensive outpatient PR program including respiratory exercises, aerobic and strengthening training

Group Type: EXPERIMENTAL

Exercise

Intervention Type: OTHER

Exercise training

Control Group

Respiratory exercises

Group Type: OTHER

Exercise

Intervention Type: OTHER

Exercise training

Interventions

Exercise

Exercise training

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients who had undergone surgery for non-small cell lung cancer in the last two years
• Patients who had no chemotherapy or radiotherapy

Exclusion Criteria

• Patients who were found unsuitable with the cardiology consultation
• Patients with psychiatric problems
• Patients with severe joint diseases
• Reluctant patients

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Izmir Katip Celebi University

OTHER

Sponsor Role: lead

Responsible Party

Ilknur Naz

Assoc. Prof

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

İlknur Naz Gürşan

Izmir, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

IKC123

Identifier Type: -

Identifier Source: org_study_id