Plasma Neurofilament Light and Its Relationship With Omega-3 Status and Soccer Heading in Women Soccer Players

NCT ID: NCT05457023

Last Updated: 2023-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

27 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-28

Study Completion Date

2023-11-09

Brief Summary

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The purpose of this study is to (1) assess how a competitive season of purposeful gameplay soccer heading in collegiate women soccer players is related to a blood biomarker for sports-related brain injury, plasma neurofilament light (NF-L), and (2) examine how a player's omega-3 status is related to plasma NF-L concentration changes during and after a competitive season of gameplay soccer heading.

Detailed Description

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Conditions

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Brain Trauma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Collegiate Women Soccer Players

National Collegiate Athletic Association (NCAA) players.

Plasma Neurofilament Light (NF-L)

Intervention Type OTHER

Plasma NF-L is a biomarker of axonal brain injury following sports-related head impacts.

Omega-3 Index

Intervention Type OTHER

Omega-3 Index is the omega-3 fatty acid content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) within the erythrocyte cell membrane. It is expressed as EPA+DHA as a percent of total identified fatty acids.

HeadCount Questionnaire

Intervention Type OTHER

HeadCount is a web-based, structured, self-administered questionnaire to assess longer-term heading exposure during competitive play and is administered bi-weekly.

Interventions

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Plasma Neurofilament Light (NF-L)

Plasma NF-L is a biomarker of axonal brain injury following sports-related head impacts.

Intervention Type OTHER

Omega-3 Index

Omega-3 Index is the omega-3 fatty acid content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) within the erythrocyte cell membrane. It is expressed as EPA+DHA as a percent of total identified fatty acids.

Intervention Type OTHER

HeadCount Questionnaire

HeadCount is a web-based, structured, self-administered questionnaire to assess longer-term heading exposure during competitive play and is administered bi-weekly.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* At least 18 years of age.
* Active player on the university's current team roster for the upcoming competitive season.
* Is eligible to participate in games and is not redshirting.

Exclusion Criteria

* Is recovering from a Physician diagnosed concussion.
* Is recovering from another injury prohibiting the study participant from participating in all sport-related activities.
Minimum Eligible Age

18 Years

Maximum Eligible Age

25 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Kansas Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Aaron Carbuhn

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Aaron F Carbuhn, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Kansas Medical Center

Locations

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University of Missouri Kansas City

Kansas City, Missouri, United States

Site Status

Rockhurst University

Kansas City, Missouri, United States

Site Status

Countries

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United States

Other Identifiers

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STUDY00148618

Identifier Type: -

Identifier Source: org_study_id

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