Exploratory Biomarker Study of Cerebrospinal Fluid in Healthy Volunteers
NCT ID: NCT01126567
Last Updated: 2010-05-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
8 participants
OBSERVATIONAL
2009-12-31
2010-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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High Sampling Rate
Samples will be obtained at a high rate
Sampling Rate
Both cohorts will have a lumbar catheter placed and CSF samples will be obtained. The only difference between the two arms will be the sampling rate of CSF. One arm will have a high sampling rate and the other will have a low sampling rate.
Low Sampling Rate
Samples will be obtained at a low rate
Sampling Rate
Both cohorts will have a lumbar catheter placed and CSF samples will be obtained. The only difference between the two arms will be the sampling rate of CSF. One arm will have a high sampling rate and the other will have a low sampling rate.
Interventions
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Sampling Rate
Both cohorts will have a lumbar catheter placed and CSF samples will be obtained. The only difference between the two arms will be the sampling rate of CSF. One arm will have a high sampling rate and the other will have a low sampling rate.
Eligibility Criteria
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Inclusion Criteria
* Judged to be in general good health based on medical history, physical exam, neuro exam, vital signs, lab profile and ECG
Exclusion Criteria
* History of bleeding disorder or deep vein thrombosis
* History of migraine or other types of headache more than twice/month, history of spinal disc disease or chronic significant low back pain
* Use of blood thinning compounds within 10 days of lumbar drain placement
* Finding on head CT that contraindicates lumbar puncture
* History of spinal surgery
* Use of tobacco/nicotine containing products within 6 month period prior to initial lumbar drain placement
18 Years
50 Years
ALL
Yes
Sponsors
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Abbott
INDUSTRY
Responsible Party
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Abbott
Principal Investigators
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Robert Lenz, M.D., Ph.D.
Role: STUDY_DIRECTOR
Abbott
Locations
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Glendale, California, United States
Countries
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Other Identifiers
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F09-113
Identifier Type: -
Identifier Source: org_study_id
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