Laparoscopic Versus Open Appendectomy in Pregnancy

NCT ID: NCT05430633

Last Updated: 2022-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

109 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-01

Study Completion Date

2022-06-01

Brief Summary

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The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.

Detailed Description

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The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.

Patients' medical records from 2010-2020 were extracted using billing information of the national health insurance fund of Estonia and ICD-10 codes (pregnancy, appendicitis).

Collected data was stored on RedCap electronic database and analyzed with R Studio.

Two group of patients were compared: pregnant patients who had laparoscopic appendectomy and pregnant patients who had open appendectomy.

Conditions

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Appendicitis Pregnancy Loss Pregnancy Preterm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Pregnant patients who underwent laparoscopic appendectomy

Pregnant patients who underwent laparoscopic appendectomy

Appendectomy

Intervention Type PROCEDURE

Appendectomy - laparoscopic or open

Pregnant patients who underwent open appendectomy

Pregnant patients who underwent open appendectomy

Appendectomy

Intervention Type PROCEDURE

Appendectomy - laparoscopic or open

Interventions

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Appendectomy

Appendectomy - laparoscopic or open

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Women with confirmed pregnancy who underwent appendectomy for acute appendicitis.

Exclusion Criteria

Women who were not pregnant when having an appendectomy
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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North Estonia Medical Centre

OTHER

Sponsor Role lead

Responsible Party

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Edgar Lipping

Principal investigator, general surgeon, MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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North Estonia Medical Centre

Tallinn, , Estonia

Site Status

Countries

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Estonia

References

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Lee SH, Lee JY, Choi YY, Lee JG. Laparoscopic appendectomy versus open appendectomy for suspected appendicitis during pregnancy: a systematic review and updated meta-analysis. BMC Surg. 2019 Apr 25;19(1):41. doi: 10.1186/s12893-019-0505-9.

Reference Type BACKGROUND
PMID: 31023289 (View on PubMed)

Prodromidou A, Machairas N, Kostakis ID, Molmenti E, Spartalis E, Kakkos A, Lainas GT, Sotiropoulos GC. Outcomes after open and laparoscopic appendectomy during pregnancy: A meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2018 Jun;225:40-50. doi: 10.1016/j.ejogrb.2018.04.010. Epub 2018 Apr 9.

Reference Type BACKGROUND
PMID: 29656140 (View on PubMed)

Zeng Q, Aierken A, Gu SS, Yao G, Apaer S, Anweier N, Wu J, Zhao JM, Li T, Tuxun T. Laparoscopic Versus Open Appendectomy for Appendicitis in Pregnancy: Systematic Review and Meta-Analysis. Surg Laparosc Endosc Percutan Tech. 2021 May 3;31(5):637-644. doi: 10.1097/SLE.0000000000000943.

Reference Type BACKGROUND
PMID: 33935257 (View on PubMed)

Other Identifiers

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345T-2

Identifier Type: -

Identifier Source: org_study_id

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