Uterine Preservation With Acar's Atony Suture for Postpartum Uterine Hemorrhage

NCT ID: NCT06353074

Last Updated: 2024-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

16 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2023-11-30

Brief Summary

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This study is aimed to show effectiveness of a new suture technique to stop postpartum uterine bleeding due to uterine atony.

Detailed Description

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A retrospective study of all women received Acar's uterine compressive atony suture between January 2021-November 2023 at a single tertiary hospital with approximately 4000 deliveries per year, was performed. The local protocol for PPH due to uterine atony is uterine manual compression, 20 IU of intravenous oxytocin in 500 cc of normal saline at 500 cc/h; 800 µg of misoprostol inserted per rectal. If additional treatment is needed, carbetocin 100mcg in 100 cc of normal saline or tranexamic acid in different posologies are used.

If uterine atony persists, intrauterine balloon tamponade or uterine compressive sutures were applied at the discretion of the physician and according to mode of delivery. When uterine compressive suture was performed, original Acar's atony suture was applied.

Conditions

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Uterine Atony With Hemorrhage Postpartum Hemorrhage

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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study group

The patients who had uterine atony during delivery and to whom Acar's atony suture were performed consisted study group.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* women without systemic disease

Exclusion Criteria

* cardiac disease
* rheumatological disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Necmettin Erbakan University

OTHER

Sponsor Role lead

Responsible Party

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Cemre Alan

Fellow of Gynecologic Oncology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ali Acar, Clinic Prof.

Role: PRINCIPAL_INVESTIGATOR

Necmettin Erbakan University

Locations

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Cemre Alan

Konya, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Say L, Chou D, Gemmill A, Tuncalp O, Moller AB, Daniels J, Gulmezoglu AM, Temmerman M, Alkema L. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014 Jun;2(6):e323-33. doi: 10.1016/S2214-109X(14)70227-X. Epub 2014 May 5.

Reference Type BACKGROUND
PMID: 25103301 (View on PubMed)

Santos RR, Martins I, Clode N, Santo S. Uterine preservation with Alcides-Pereira's compressive sutures for postpartum uterine atony. Eur J Obstet Gynecol Reprod Biol. 2022 Oct;277:27-31. doi: 10.1016/j.ejogrb.2022.08.008. Epub 2022 Aug 12.

Reference Type BACKGROUND
PMID: 35987075 (View on PubMed)

Balki M, Wong CA. Refractory uterine atony: still a problem after all these years. Int J Obstet Anesth. 2021 Nov;48:103207. doi: 10.1016/j.ijoa.2021.103207. Epub 2021 Jul 21.

Reference Type BACKGROUND
PMID: 34391025 (View on PubMed)

Bateman BT, Berman MF, Riley LE, Leffert LR. The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries. Anesth Analg. 2010 May 1;110(5):1368-73. doi: 10.1213/ANE.0b013e3181d74898. Epub 2010 Mar 17.

Reference Type BACKGROUND
PMID: 20237047 (View on PubMed)

Al-Zirqi I, Vangen S, Forsen L, Stray-Pedersen B. Prevalence and risk factors of severe obstetric haemorrhage. BJOG. 2008 Sep;115(10):1265-72. doi: 10.1111/j.1471-0528.2008.01859.x.

Reference Type BACKGROUND
PMID: 18715412 (View on PubMed)

Ramler PI, van den Akker T, Henriquez DDCA, Zwart JJ, van Roosmalen J, van Lith JMM, van der Bom JG; TeMpOH-1 study group. Women receiving massive transfusion due to postpartum hemorrhage: A comparison over time between two nationwide cohort studies. Acta Obstet Gynecol Scand. 2019 Jun;98(6):795-804. doi: 10.1111/aogs.13542. Epub 2019 Feb 11.

Reference Type BACKGROUND
PMID: 30667050 (View on PubMed)

Huque S, Roberts I, Fawole B, Chaudhri R, Arulkumaran S, Shakur-Still H. Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial. BMC Pregnancy Childbirth. 2018 May 29;18(1):186. doi: 10.1186/s12884-018-1829-7.

Reference Type BACKGROUND
PMID: 29843627 (View on PubMed)

B-Lynch C, Coker A, Lawal AH, Abu J, Cowen MJ. The B-Lynch surgical technique for the control of massive postpartum haemorrhage: an alternative to hysterectomy? Five cases reported. Br J Obstet Gynaecol. 1997 Mar;104(3):372-5. doi: 10.1111/j.1471-0528.1997.tb11471.x.

Reference Type BACKGROUND
PMID: 9091019 (View on PubMed)

Nelson WL, O'Brien JM. The uterine sandwich for persistent uterine atony: combining the B-Lynch compression suture and an intrauterine Bakri balloon. Am J Obstet Gynecol. 2007 May;196(5):e9-10. doi: 10.1016/j.ajog.2006.10.887.

Reference Type BACKGROUND
PMID: 17466689 (View on PubMed)

Baskett TF. Uterine compression sutures for postpartum hemorrhage: efficacy, morbidity, and subsequent pregnancy. Obstet Gynecol. 2007 Jul;110(1):68-71. doi: 10.1097/01.AOG.0000267499.40531.a4.

Reference Type BACKGROUND
PMID: 17601898 (View on PubMed)

Acar A, Ercan F, Pekin A, Elci Atilgan A, Sayal HB, Balci O, Gorkemli H. Conservative management of placental invasion anomalies with an intracavitary suture technique. Int J Gynaecol Obstet. 2018 Nov;143(2):184-190. doi: 10.1002/ijgo.12593. Epub 2018 Aug 13.

Reference Type BACKGROUND
PMID: 29989156 (View on PubMed)

Pereira A, Nunes F, Pedroso S, Saraiva J, Retto H, Meirinho M. Compressive uterine sutures to treat postpartum bleeding secondary to uterine atony. Obstet Gynecol. 2005 Sep;106(3):569-72. doi: 10.1097/01.AOG.0000168434.28222.d3.

Reference Type BACKGROUND
PMID: 16135589 (View on PubMed)

Moleiro ML, Braga J, Machado MJ, Guedes-Martins L. Uterine Compression Sutures in Controlling Postpartum Haemorrhage: A Narrative Review. Acta Med Port. 2022 Jan 3;35(1):51-58. doi: 10.20344/amp.11987. Epub 2019 Oct 7.

Reference Type BACKGROUND
PMID: 32208130 (View on PubMed)

Acar A, Alan C, Dogru S. A new technique: Acar's atony suture for postpartum uterine hemorrhage. Z Geburtshilfe Neonatol. 2025 Jun;229(3):195-200. doi: 10.1055/a-2441-6846. Epub 2024 Nov 11.

Reference Type DERIVED
PMID: 39529317 (View on PubMed)

Other Identifiers

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1335cemre.

Identifier Type: -

Identifier Source: org_study_id

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