Laparoscopic Value in the Management of Acute Abdomen During Pregnancy

NCT ID: NCT05407922

Last Updated: 2022-06-07

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-06-30
• Study Completion Date: 2023-03-31

Brief Summary

The term "acute abdomen" is often used to describe the manifestations of any serious intraperitoneal disease, which may indicates surgical intervention. Acute abdomen in pregnancy accounts for approximately 7-10% of all abdominal emergencies.

Several pathologies could contribute acute abdominal pain during pregnancy. They include obstetric and non-obstetric causes. As for the non-obstetric causes , any gastrointestinal or urological disorders could be presented by an acute abdominal pain.

In pregnancy, several factors overlap and making the diagnosis challenging. These factors include the distorted anatomy by the growing uterus that displaces intraperitoneal structures. Additionally, nausea, vomiting, and abdominal pain are considered the normal course during pregnancy especially at the first trimester. Moreover, sure diagnosis must be achieved to operate in a pregnant woman with more possible morbidity and mortality for the mother and\or fetus.

Detailed Description

Laparoscopy can be safely performed during any trimester of pregnancy. Historical recommendations were to limit surgery to the second trimester only, but these recommendations were based on experience with open surgical procedures during pregnancy. These recommendations were thought to minimize the spontaneous abortion rate of surgical intervention during the first trimester, which was reported to be as high as 12%, and to avoid preterm labor, reported in up to 40%, when surgery occurred during the third trimester. However, studies limited to laparoscopy have shown improved outcomes and demonstrated that pregnant patients may undergo laparoscopic surgery safely during any trimester without any appreciated increase in risk to the mother or fetus.

Conditions

Acute Abdomen; Pregnancy Related

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Laparoscopy Group

The laparoscopy group included every pregnant woman having laparoscopic intervention because of acute abdominal pain during any trimester of her pregnancy.

Laparoscopy vs Non-laparoscopy approach

Intervention Type: PROCEDURE

Pregnant women who will undergo a laparoscopic or open surgical exploration of the abdomen

Non-laparoscopy Group

Non-laparoscopy Group included every pregnant woman having treatment approach other than the laparoscopic approach because of acute abdominal pain.

Laparoscopy vs Non-laparoscopy approach

Intervention Type: PROCEDURE

Pregnant women who will undergo a laparoscopic or open surgical exploration of the abdomen

Interventions

Laparoscopy vs Non-laparoscopy approach

Pregnant women who will undergo a laparoscopic or open surgical exploration of the abdomen

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• All pregnant women having acute abdomen and underwent surgical intervention will be included in this study.

Exclusion Criteria

• Non-pregnant women with acute abdomen are excluded.

• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Sohag University

OTHER

Sponsor Role: lead

Responsible Party

Emad Ali Ahmed Ali

Lecturer

Responsibility Role: PRINCIPAL_INVESTIGATOR

References

Augustin G, Majerovic M. Non-obstetrical acute abdomen during pregnancy. Eur J Obstet Gynecol Reprod Biol. 2007 Mar;131(1):4-12. doi: 10.1016/j.ejogrb.2006.07.052. Epub 2006 Sep 18.

Reference Type: BACKGROUND

PMID: 16982130 (View on PubMed)

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Reference Type: BACKGROUND

PMID: 32295644 (View on PubMed)

Zachariah SK, Fenn M, Jacob K, Arthungal SA, Zachariah SA. Management of acute abdomen in pregnancy: current perspectives. Int J Womens Health. 2019 Feb 8;11:119-134. doi: 10.2147/IJWH.S151501. eCollection 2019.

Reference Type: BACKGROUND

PMID: 30804686 (View on PubMed)

Jackson H, Granger S, Price R, Rollins M, Earle D, Richardson W, Fanelli R. Diagnosis and laparoscopic treatment of surgical diseases during pregnancy: an evidence-based review. Surg Endosc. 2008 Sep;22(9):1917-27. doi: 10.1007/s00464-008-9989-6. Epub 2008 Jun 14.

Reference Type: BACKGROUND

PMID: 18553201 (View on PubMed)

Other Identifiers

soh-med-42342

Identifier Type: -

Identifier Source: org_study_id