Effectiveness of Engaging in Advance Care Planning Talks (ENACT) Group Visits in Primary Care for Older Adults With and Without Alzheimer's Disease

NCT ID: NCT05421728

Last Updated: 2025-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

516 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-07-26

Study Completion Date

2027-05-01

Brief Summary

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The main goal of the ENACT (ENgaging in Advance Care planning Talks) Group Visit intervention is to integrate a patient-centered advance care planning process into primary care, ultimately helping patients to receive medical care that is aligned with their values. The ENACT Group Visit intervention involves two group discussions about advance care planning with 8-10 patients who meet for 2-hour sessions, one month apart, facilitated by a geriatrician and a social worker. This study will compare the ENACT Group Visit intervention to mailed advance care planning materials.

Detailed Description

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This pilot feasibility randomized controlled study will determine the feasibility, acceptability and preliminary efficacy of the ENACT Group Visit intervention compared to a comparison arm.

The ENACT Group Visit intervention aims to engage patients in an interactive discussion of key ACP concepts and support patient-initiated ACP actions (i.e. choosing decision-maker(s), deciding on preferences during serious illness, discussing preferences with decision-makers and healthcare providers, and documenting advance directives). The group visits involve two 2-hour sessions, one month apart, facilitated by a geriatrician and a social worker. The ENACT Group Visit is based on an intervention manual that guides the structure, facilitator considerations, session format, and documentation and billing details. The discussions include sharing experiences related to ACP, considering values related to serious illness, choosing a surrogate decision-maker(s), flexibility in decision making, and having conversations with decision-makers and healthcare providers. The facilitators support an interactive discussion that promotes opportunities for patients to learn from others' experiences.

Conditions

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Advance Care Planning Primary Health Care

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Trial
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Participants: ENACT Group Visit

Participants will engage in two 2-hour group visits related to advance care planning, including printed advance care planning resources.

Group Type EXPERIMENTAL

ENACT group visit

Intervention Type BEHAVIORAL

Participation in two 2 hour group visits about advance care planning.

Participants: Mailed Resources

Participants will receive printed advance care planning resources by mail.

Group Type ACTIVE_COMPARATOR

Mailed Resources

Intervention Type BEHAVIORAL

Participants will receive advance care planning resources in the mail with instructions to follow up with their primary care provider.

Clinic Stakeholders

Clinic stakeholders providing care for participants enrolled in the "Participants: Enact Group Visits" arm. Demographics, and adverse event data will not be collected for this arm.

Group Type NO_INTERVENTION

No interventions assigned to this group

Caregivers

Caregivers will be consented via postcard consent to facilitate patient participants' engagement in the trial and group visits. Outcome measure, demographics, and adverse event data will not be collected for this arm, however caregivers will assist participants in providing outcome measure data (responding to surveys, etc.)

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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ENACT group visit

Participation in two 2 hour group visits about advance care planning.

Intervention Type BEHAVIORAL

Mailed Resources

Participants will receive advance care planning resources in the mail with instructions to follow up with their primary care provider.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 70 or older
* At least one clinic visit in past year
* No advanced care planning (ACP) document in electronic health record based on a clinic-level, population-based report
* Preferred language English for UCHealth clinics or preferred language English or Spanish for Denver Health clinic


* Age 18 and older
* Preferred language English for UCHealth clinics or preferred language English or Spanish for Denver Health clinic
* Patient with potential cognitive impairment consented to participate in study


* Work as a multidisciplinary team member at a participating primary care clinic in the study
* English speaking as a preferred language
* Invited to participate in interviews or focus groups after the ENACT Group Visits intervention

Exclusion Criteria

* Inability to demonstrate informed consent
* Does not have ready access to a telephone
* Inability to travel to clinic
* Moving out of area in 6 months
* Inability to participate in group visits due to hearing impairment as determined by clinic and/or study staff
* A household member (same address) is already enrolled

Caregivers


* Does not have ready access to a telephone
* Inability to travel to clinic
* Moving out of area in 6 months
* Inability to participate in group visits due to hearing impairment as determined by clinic and/or study staff

Clinic Stakeholders


\- Inability to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute on Aging (NIA)

NIH

Sponsor Role collaborator

University of Colorado, Denver

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hillary Lum, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Colorado, Denver

Locations

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UCHealth

Aurora, Colorado, United States

Site Status

UC Health Boulder Family Medicine

Boulder, Colorado, United States

Site Status

Denver Health Westside Clinic

Denver, Colorado, United States

Site Status

UC Health Lowry Internal Medicine

Denver, Colorado, United States

Site Status

UC Health AF Williams Family Medicine

Denver, Colorado, United States

Site Status

UC Health Lone Tree Seniors

Lone Tree, Colorado, United States

Site Status

UC Health Lone Tree Primary Care

Lonetree, Colorado, United States

Site Status

UC Health Westminster Primary Care

Westminster, Colorado, United States

Site Status

Countries

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United States

References

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Lum HD, Jones J, Matlock DD, Glasgow RE, Lobo I, Levy CR, Schwartz RS, Sudore RL, Kutner JS. Advance Care Planning Meets Group Medical Visits: The Feasibility of Promoting Conversations. Ann Fam Med. 2016 Mar;14(2):125-32. doi: 10.1370/afm.1906.

Reference Type BACKGROUND
PMID: 26951587 (View on PubMed)

Farro SA, Juarez-Colunga E, Patel C, Bettcher BM, Haynes CA, Huebschmann AG, Nowels D, Tietbohl CK, Shi J, Ritger C, Shanbhag P, Resman K, Sudore RL, Lum HD. Engaging English- and Spanish-speaking older adults with and without possible cognitive impairment in advance care planning group visits: protocol for the ENgaging in Advance Care Planning Talks (ENACT) randomized controlled trial. Trials. 2025 Sep 25;26(1):353. doi: 10.1186/s13063-025-08964-x.

Reference Type DERIVED
PMID: 40999430 (View on PubMed)

Lum H, Farro S, Juarez-Colunga E, Patel C, Bettcher B, Haynes C, Huebschmann A, Nowels D, Tietbohl C, Shi J, Ritger C, Shanbhag P, Resman K, Sudore R. Engaging English- and Spanish-speaking older adults with and without possible cognitive impairment in advance care planning group visits: Protocol for the ENgaging in Advance Care Planning Talks (ENACT) Randomized Controlled Trial. Res Sq [Preprint]. 2025 Jun 20:rs.3.rs-6560971. doi: 10.21203/rs.3.rs-6560971/v1.

Reference Type DERIVED
PMID: 40585266 (View on PubMed)

Provided Documents

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Document Type: Informed Consent Form: English Consent Form

View Document

Document Type: Informed Consent Form: Spanish Consent From

View Document

Other Identifiers

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R01AG066804

Identifier Type: NIH

Identifier Source: secondary_id

View Link

20-1978

Identifier Type: -

Identifier Source: org_study_id

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