"Outwalk MS" - Benefits of Outdoor Walking in Multiple Sclerosis
NCT ID: NCT05415956
Last Updated: 2023-09-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
60 participants
INTERVENTIONAL
2021-11-01
2022-11-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Few studies have nevertheless examined the effects of outdoor walking exercise therapy in pwMS. The purpose of the present study is therefore to examine the effects of 7 weeks of moderate-to-high intensity outdoor walking exercise therapy on walking capacity (primary outcome: 6-minute walk test) and well-being in pwMS.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Increasing Physical Activity for Adults With Multiple Sclerosis (MS)
NCT06270641
Exercise in Multiple Sclerosis
NCT02716701
Internet-based Physical Activity Promotion and Exercise Prescription for People With Multiple Sclerosis (Feasibility Study)
NCT04057066
In Clinic Physical Activity in Persons With Multiple Sclerosis
NCT04186910
Exercise-based Therapy for Multiple Sclerosis Patients
NCT03735524
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
The investigators will perform a cluster randomization (computer generated random numbers) according to cities across Denmark (when 4-12 pwMS are interested and eligible).
Waitlist/control group will be offered the same outdoor walking exercise therapy after the initial 7 weeks.
24 weeks after the walking exercise intervention, a follow-up test will be carried out as well.
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Walking exercise therapy
7 week intervention group. 6-12 persons per group. 2 sessions per week, 14 sessions in total.
Surface: the investigators aim to involve as much forest/gravel trails as possible, with up/down hill walking.
Uneven session numbers: warm-up (6 minutes at BORG 10-11), continous walking (starting at 12-20 minutes at BORG 13-14 and progressing to 20-40 minutes at BORG 15-16, adjusted according to the starting level of each participant) and cool-down (approximately 10 minutes at BORG 10-11).
Even session numbers: warm-up (6 minutes at BORG 10-11), intermittent walking (starting at 3-4 intervals of 2 minutes at BORG 14-15 and progressing to 4-5 intervals of 2-3 minutes at BORG 16-17; with all intervals being interspersed by 1 minute rest) and cool-down (approximately 10 minutes at BORG 10-11).
Walking exercise therapy
Moderate-to-high intensity walking exercise therapy (7 weeks, 14 session) with progression in duration and intensity.
Control/Waitlist
7 week control/waitlist group. Continuation of habitual lifestyle during the 7 week intervention period (yet these participants will receive the exact walking exercise therapy afterwards).
No interventions assigned to this group
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Walking exercise therapy
Moderate-to-high intensity walking exercise therapy (7 weeks, 14 session) with progression in duration and intensity.
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* self-reported clinical MS diagnosis
* PDDS ≤ 4 (corresponding to preserved walking capacity without assistive devices of at least 10 m)
* able to independently attend the testing
Exclusion Criteria
* recent (6 months retrospective) fractures, amputation or other critical physical impairments that eliminates participation in the described training study
* participation in structured exercise therapy (including walking) for the past 3 months (≥ 2 session per week of moderate-to-high intensity)
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
The Danish MS Society
UNKNOWN
University of Aarhus
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Lars G Hvid, MSc, PhD
Role: PRINCIPAL_INVESTIGATOR
Aarhus University, Department of Public Health, Exercise Biology
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Aarhus University, Health, Exercise Biology
Aarhus, Jutland, Denmark
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Hvid LG, Steenberg JL, Roy F, Skovgaard L. Outdoor walking exercise therapy improves walking capacity and well-being in persons with multiple sclerosis: A randomized controlled trial. Ann Phys Rehabil Med. 2025 Apr 18;68(6):101985. doi: 10.1016/j.rehab.2025.101985. Online ahead of print.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Outwalk_MS
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.