Recruitment Maneuver After Bronchoalveolar Lavage in ARDS Patients

NCT ID: NCT05372731

Last Updated: 2022-10-28

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-11-30
• Study Completion Date: 2022-12-30

Brief Summary

ARDS caused by pneumonia is one of the main reasons for ICU admission in critically ill patients, and also a common complication in patients admitted to ICU with invasive mechanical ventilation. Bronchoalveolar lavage (BAL) is the main diagnostic method for these patients, which often leads to alveolar collapse and exacerbates hypoxemia. In clinical practice, recruitment maneuver (RM) is often used immediately after BAL to prevent such a situation, but there is a lack of data on RM after BAL.

Conditions

Acute Respiratory Distress Syndrome

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

RM after BAL

patients underwent RM after BAL

Group Type: EXPERIMENTAL

Recruitment Maneuver

Intervention Type: OTHER

RM after BAL

Non-RM after BAL

patients did not undergo RM after BAL

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Recruitment Maneuver

RM after BAL

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. Adult patients with invasive mechanical ventilation;

2. Patients who diagnosed with ARDS according to the Berlin definition

3. There are indications for bronchoalveolar lavage

Exclusion Criteria

1. Patients with contraindications for EIT procedures;

2. Patients with contraindications for RM;

3. Previous chronic respiratory diseases (long-term home oxygen therapy for chronic respiratory diseases such as pulmonary fibrosis or COPD);

4. Pregnancy;

5. Refusal to sign informed consent

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Southeast University, China

OTHER

Sponsor Role: lead

Responsible Party

Ling Liu

Director of Intensive Care Unit, Principal Investigator, Clinical Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

ling liu, phD

Role: PRINCIPAL_INVESTIGATOR

Zhongda Hospital

Central Contacts

ling liu, phD

Role: CONTACT

liulingdoctor@126.com

86-25-83272201

ling liu, phD

Role: CONTACT

86-25-83272201

Other Identifiers

BAL20220420

Identifier Type: -

Identifier Source: org_study_id