SCOOT: Sample Collection for DART

NCT ID: NCT05368298

Last Updated: 2025-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-08-11

Study Completion Date

2025-12-31

Brief Summary

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The study will use a blood sample collected from participants to:

* Develop new ways of finding and diagnosing lung health problems, such as lung cancer.
* Develop tools which make it easier to screen people with possible lung health problems, diagnose problems earlier and with fewer tests, and start the best treatment faster.
* Help improve the early diagnosis of lung cancer, as finding lung cancer early means that it can be treated more easily and successfully.

Detailed Description

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The results from this study will be linked with the data from the DART study (also collecting data through the Lung Health Check programme) to develop new ways of using computer technology (artificial intelligence) to improve lung health care. The studies use computer programs (called 'algorithms') which can be trained to analyse medical samples. Once developed, these algorithms can be used to support doctors by increasing their speed and accuracy of diagnosing issues.

Conditions

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Lung Cancer

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

1. Patients with a pulmonary nodule or nodule(s) detected on a CT scan performed as part of Lung Cancer Screening from the Lung Health Check centres, that require further investigation with a PET-CT scan, and / or biopsy, and / or resection
2. Willing and able to give informed consent

Exclusion Criteria

* None -
Minimum Eligible Age

55 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Innovate UK

OTHER_GOV

Sponsor Role collaborator

Optellum

UNKNOWN

Sponsor Role collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

Sponsor Role collaborator

Cancer Research UK

OTHER

Sponsor Role collaborator

GE Healthcare

INDUSTRY

Sponsor Role collaborator

Prenostics

UNKNOWN

Sponsor Role collaborator

Roche Diagnostics GmbH

INDUSTRY

Sponsor Role collaborator

University of Oxford

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Richard Lee

Role: PRINCIPAL_INVESTIGATOR

Royal Marsden NHS Foundation Trust

Locations

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Lung Health Check: Oxford - Churchill Hospital, OUH

Oxford, Oxfordshire, United Kingdom

Site Status RECRUITING

Lung Health Check Centre: Royal Sussex

Brighton, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: North Bristol

Bristol, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: Gateshead

Gateshead, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: Corby & Kettering

Kettering, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: Cheshire & Merseyside

Liverpool, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: RM Partners

London, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: Newcastle & Gateshead

Newcastle, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: Plymouth

Plymouth, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: Stoke

Stoke, , United Kingdom

Site Status RECRUITING

Lung Health Check Centre: South Tyneside and Sunderland

Sunderland, , United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Rachel Austin

Role: CONTACT

01865 617420

Facility Contacts

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Sajal Porwal

Role: primary

+44 1865 226425

Jenny Messenger

Role: primary

Anna Bibby

Role: primary

Ruth Sharrock

Role: primary

George Tsaknis

Role: primary

Martin Ledson

Role: primary

Richard Lee

Role: primary

Liz Fuller

Role: primary

Cyrus Daneshvar

Role: primary

Imran Hussain

Role: primary

Nadia Elkaram

Role: primary

Related Links

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https://www.cancerresearchuk.org/about-cancer/lung-cancer/getting-diagnosed/lung-health-checks

Cancer Research UK webpage containing information about the Lung Health Check programme

Other Identifiers

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OCTO-106

Identifier Type: -

Identifier Source: org_study_id

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