Risk Factor for Readmission and Death of Lower Respiratory Infections in Older Adults

NCT ID: NCT05355324

Last Updated: 2022-05-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

215 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-03-01

Study Completion Date

2021-12-31

Brief Summary

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Lower respiratory tract infection(LRTI) is a prevalent disease that threatens the health of older people worldwide. Anemia is also a common disorder in the elderly, and its prevalence increases significantly with age. Most factors that contribute to the development of anemia are improvable. Therefore, we investigated whether anemia was a risk factor for LRTI-caused readmission and death in the elderly occurring within 1 year of discharge from the hospital.

Detailed Description

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Objectives: To investigate the effect of anemia on readmission and deaths in the older adults following lower respiratory tract infection (LRTI)-caused hospitalization.

Design: A retrospective cohort study. Setting and Participants: Older patients (age: ≥ 80 years) hospitalized at the Department of Geriatrics, from March 2016 to December 2019 to undergo treatment for LRTIs were included.

Methods: The patients were divided into two groups (anemia and non-anemia) based on the level of hemoglobin. They were kept under observation till the occurrence of mortality event or 1 year after discharge. The primary follow-up outcome was LRTI-caused readmission and/or death.

Conditions

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Lower Respiratory Infection Anemia Readmission Death

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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anemia

patients with anemia

no intervention

Intervention Type OTHER

no intervention

non-anemia

patients without anemia

no intervention

Intervention Type OTHER

no intervention

Interventions

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no intervention

no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 80 years
* lower respiratory tract infection

Exclusion Criteria

* Died at the time of first admission
* Active malignancy
* Tuberculosis
* Anemia caused by gastrointestinal bleeding of unknown origin
* Achalasia of the cardia
* Could not be followed up after discharge
* Data were missing
Minimum Eligible Age

80 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Tongren Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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He Y, Chen Y, Cao K, Zheng H. Effect of Anemia on Readmission and Death in Octogenarian Patients with Lower Respiratory Tract Infections: A Retrospective Cohort Study. Int J Clin Pract. 2022 Oct 27;2022:4566936. doi: 10.1155/2022/4566936. eCollection 2022.

Reference Type DERIVED
PMID: 36349057 (View on PubMed)

Other Identifiers

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YuHe_1987

Identifier Type: -

Identifier Source: org_study_id

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