Optical Coherence Tomography Angiography and Choroidal Osteoma

NCT ID: NCT05342324

Last Updated: 2022-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

28 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-06-01

Study Completion Date

2022-01-31

Brief Summary

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This study evaluates the vessel density of choriocapillary vascular network in eyes affected by choroidal osteoma and in eyes complicated by choroidal neovascularization, using optical coherence tomography angiography.

Detailed Description

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The choroidal osteoma is a rare benign tumor of choroid, it is bilateral in 10%-25% of cases, affecting usually young women. Previous studies evaluated the morphologic characteristics of tumor-related vasculatures, described as a seafun vascular networks, but none focused on study of vessel density of coriocapillary.

The aim of this study is to investigate the potential role of the optical coherence tomography angiography (OCTA) in evaluating the choriocapillary vessel density in order to individuate the changes of this vascular network that may influence the onset of choroidal neovasculariztion.

Therefore, OCTA could be useful in the clinical management of the choroidal osteoma

Conditions

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Choroidal Osteoma, Bilateral

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Optical coherence tomography angiography

To evaluate the vessel density in choriocapillary vascular networks, using optical coherence tomography angiography

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* age older than 50 years
* diagnosis of choroidal osteoma
* absence of history of vitreoretinal and vascular retinal diseases

Exclusion Criteria

* age younger than 50 years
* no diagnosis of choroidal osteoma
* presence of history of vitreoretinal and vascular retinal diseases
Minimum Eligible Age

50 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Federico II University

OTHER

Sponsor Role lead

Responsible Party

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Gilda Cennamo

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gilda Cennamo

Role: PRINCIPAL_INVESTIGATOR

Università Federico II

Locations

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Federico II University

Naples, Napoli, Italy

Site Status

Countries

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Italy

References

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Cennamo G, Iacucci G, Breve MA, Montorio D, Xompero C, Costagliola C. The role of choriocapillaris vessel density in the pathogenesis of macular neovascularization associated with choroidal osteoma. Graefes Arch Clin Exp Ophthalmol. 2023 May;261(5):1283-1287. doi: 10.1007/s00417-022-05921-1. Epub 2022 Dec 1.

Reference Type DERIVED
PMID: 36454322 (View on PubMed)

Other Identifiers

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1604/21

Identifier Type: -

Identifier Source: org_study_id

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