OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients

NCT ID: NCT05455567

Last Updated: 2022-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

57 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-01

Study Completion Date

2022-05-15

Brief Summary

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The aim of the present study was to examine and measure SFCT and CCVD using respectively EDI-OCT and OCTA in preperimetric and advanced glaucomatous eyes, in order to shed light on the vascular pathogenesis of glaucoma disease.

Detailed Description

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Conditions

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Glaucoma Open-Angle Primary

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with pre perimetric open angle glaucoma

OCTA

Intervention Type DIAGNOSTIC_TEST

Choriocapillary vessel density calculated with OCTA

patients with perimetric open angle glaucoma

OCTA

Intervention Type DIAGNOSTIC_TEST

Choriocapillary vessel density calculated with OCTA

healthy patients

OCTA

Intervention Type DIAGNOSTIC_TEST

Choriocapillary vessel density calculated with OCTA

Interventions

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OCTA

Choriocapillary vessel density calculated with OCTA

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* diagnosis of glaucoma
* absence of diabetes, heart diseases, hypertension
* absence of drug intake
* absence of vitreoretinal, vascular retinal diseases
* absence of previous ocular surgery and congenital eye diseases.
* absence of errors of refraction
* absence of lens opacities
* absence of low-quality OCT and OCTA images

Exclusion Criteria

* age younger than 40 years
* presence of diabetes, heart diseases, hypertension
* vitreoretinal and vascular retinal diseases
* previous ocular surgery and congenital eye diseases
* errors of refraction
* lens opacities
* low-quality OCT and OCTA images
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Federico II University

OTHER

Sponsor Role lead

Responsible Party

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Gilda Cennamo

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Naples "Federico II"

Naples, , Italy

Site Status

Countries

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Italy

Other Identifiers

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0102/22

Identifier Type: -

Identifier Source: org_study_id

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