OCTA and Retinal Angiomatous Proliferation

NCT ID: NCT04689789

Last Updated: 2020-12-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

118 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-01

Study Completion Date

2020-12-20

Brief Summary

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To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.

Detailed Description

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Retinal vascular anomalous complex represents a distinct form of neovascularization in patients with age-related macular degeneration.

The study investigated the changes in retinal vascular network using optical coherence tomography angiography, a novel and non invasive diagnostic technique that allows to better understand the pathophysiologic mechanism of this neovascularization.

Conditions

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Age Related Macular Degeneration

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with RAP

Patients with previous diagnosis of retinal angiomatous proliferation

optical coherence tomography angiography

Intervention Type DIAGNOSTIC_TEST

optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network

Patients with reticular pseudodrusen

Patients with previous diagnosis of reticular pseudodrusen

optical coherence tomography angiography

Intervention Type DIAGNOSTIC_TEST

optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network

Control group

Healthy eyes without actual and previous ocular diseases

optical coherence tomography angiography

Intervention Type DIAGNOSTIC_TEST

optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network

Interventions

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optical coherence tomography angiography

optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* age older than 65 years
* diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
* absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
* absence of significant lens opacities, low-quality OCT-A images.

Exclusion Criteria

* age older than 80 years
* absence of diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
* presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
* presence of significant lens opacities, low-quality OCT-A images.
Minimum Eligible Age

65 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Federico II University

OTHER

Sponsor Role lead

Responsible Party

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Gilda Cennamo

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gilda Cennamo

Role: PRINCIPAL_INVESTIGATOR

Federico II University

Locations

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Federico II University

Naples, Napoli, Italy

Site Status

Countries

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Italy

Other Identifiers

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2912/20

Identifier Type: -

Identifier Source: org_study_id