C-BRACE Versus SCO in Community Ambulators

NCT ID: NCT05332509

Last Updated: 2023-06-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-19

Study Completion Date

2023-04-17

Brief Summary

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The purpose of this multicentric study is to assess the impact of C-BRACE on mobility, endurance, confidence, participation, satisfaction, psychosocial adjustment and quality of life in community ambulators using a Stance Control Orthosis.

Detailed Description

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During two months of inclusion period, the investigators invite all patients matching with inclusion criteria for an enrolment visit, collect written consent and record general patient information. The eCRF (electronic Case Report Form) assigns the enrolled patient into one group for the trial (C-BRACE/SCO or SCO/C-BRACE), in a randomized order. The assessments are performed after 2 month follow-up period with each orthosis with a minimal wash-out period of 2 weeks.

Conditions

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Lower Limb Pareses

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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C-BRACE/SCO

The patient is first fitted during 2 months with the C-BRACE orthosis, them, after 2 weeks wash-out period, the patient is fitted with its Stance Controlled Orthosis (SCO).

Group Type EXPERIMENTAL

C-BRACE

Intervention Type DEVICE

The C-BRACE is a custom made Knee-Ankle-Foot-Orthosis with a microprocessor-controlled hydraulic knee-joint articulation. The C-BRACE technology offers to a patient with knee locking deficiencies the following advantages: approximation of the physiological gait pattern, stability while standing and walking, adaptation to various surfaces, inclines, gait situations and walking speeds.

SCO

Intervention Type DEVICE

The SCO is a custom made Knee-Ankle-Foot-Orthosis with a knee-joint locked during stance phase and released during swing phase.

SCO/C-BRACE

The patient is using its Stance controlled orthosis (SCO) during 2 months, then, after 2 weeks wash-out period, the patient is fitted with the C-BRACE orthosis.

Group Type OTHER

C-BRACE

Intervention Type DEVICE

The C-BRACE is a custom made Knee-Ankle-Foot-Orthosis with a microprocessor-controlled hydraulic knee-joint articulation. The C-BRACE technology offers to a patient with knee locking deficiencies the following advantages: approximation of the physiological gait pattern, stability while standing and walking, adaptation to various surfaces, inclines, gait situations and walking speeds.

SCO

Intervention Type DEVICE

The SCO is a custom made Knee-Ankle-Foot-Orthosis with a knee-joint locked during stance phase and released during swing phase.

Interventions

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C-BRACE

The C-BRACE is a custom made Knee-Ankle-Foot-Orthosis with a microprocessor-controlled hydraulic knee-joint articulation. The C-BRACE technology offers to a patient with knee locking deficiencies the following advantages: approximation of the physiological gait pattern, stability while standing and walking, adaptation to various surfaces, inclines, gait situations and walking speeds.

Intervention Type DEVICE

SCO

The SCO is a custom made Knee-Ankle-Foot-Orthosis with a knee-joint locked during stance phase and released during swing phase.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* person with knee locking deficiency
* person using a SCO (Stance Control Orthosis) for at least three months, walking with a swing phase on a flat ground, without walking aid or with one cane or one crutch.
* person having the ability to walk at 3km/h (measured with 10 meters walk test) with the SCO in unlocked mode.
* person with a stable stance phase on the contralateral side

Exclusion Criteria

* person with deficient or unstable contralateral knee, including person using a Knee-Ankle Foot Orthosis on the contralateral limb
* person walking using two canes, two crutches, one or two underarm crutches or a walker
* person with health condition not compatible with the study protocol
* person under 18 years old
* person unwilling / unable to follow the entire study protocol / instructions
* person who did not give her written consent to participate to the study or unable to personally give her consent
* person with knee and/or hip flexion contracture \>10°
* person with genu varum / valgum \> 10° (not reducible)
* person with moderate to severe spasticity
* person with leg length discrepancy \> 15cm
* person who necessitate the use of an orthoprosthesis
* person with body weight \> 125kg
* person with unstable trunk in standing position
* person with cognitive impairments
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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EVAMED

OTHER

Sponsor Role collaborator

Otto Bock France SNC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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François GENET, Prof. med

Role: STUDY_CHAIR

CHU Raymond Poincaré Garches France

Frank BRAATZ, Prof. med

Role: STUDY_CHAIR

PFH Private Hochschule Göttingen Germany

Axel RUETZ, Dr. med.

Role: STUDY_CHAIR

Katholisches Klinikum Koblenz-Montabaur Germany

Locations

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CRF Korian Le Mont Veyrier

Argonay, , France

Site Status

Centre Jacques Calvé Fondation Hopale

Berck, , France

Site Status

HIA Percy

Clamart, , France

Site Status

Pôle de Réadaptation de Cornouaille

Concarneau, , France

Site Status

Centre Hospitalier Dieppe

Dieppe, , France

Site Status

Hôpital Raymond-Poincaré

Garches, , France

Site Status

Hia Laveran

Marseille, , France

Site Status

IRR Louis Pierquin

Nancy, , France

Site Status

CRRF La Chataigneraie

Paris, , France

Site Status

CRRF Léopold Bellan

Paris, , France

Site Status

Centre Bouffard Vercelli

Perpignan, , France

Site Status

CRRF La Tourmaline

Saint-Herblain, , France

Site Status

CRF Salies de Béarn

Salies-de-Béarn, , France

Site Status

LADAPT Thionis

Thionville, , France

Site Status

Chu Rangueil

Toulouse, , France

Site Status

IRMA Institut Robert Merle d'Aubigné

Valenton, , France

Site Status

PFH Private Hochschule Göttingen

Göttingen, , Germany

Site Status

Katholisches Klinikum Koblenz-Montabaur

Koblenz, , Germany

Site Status

Countries

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France Germany

References

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Deems-Dluhy S, Hoppe-Ludwig S, Mummidisetty CK, Semik P, Heinemann AW, Jayaraman A. Microprocessor Controlled Knee Ankle Foot Orthosis (KAFO) vs Stance Control vs Locked KAFO: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2021 Feb;102(2):233-244. doi: 10.1016/j.apmr.2020.08.013. Epub 2020 Sep 22.

Reference Type BACKGROUND
PMID: 32976844 (View on PubMed)

Karatzios C, Loiret I, Luthi F, Leger B, Le Carre J, Saubade M, Muff G, Benaim C. Transcultural adaptation and validation of a French version of the Prosthetic Limb Users Survey of Mobility 12-item Short-Form (PLUS-M/FC-12) in active amputees. Ann Phys Rehabil Med. 2019 May;62(3):142-148. doi: 10.1016/j.rehab.2019.02.006. Epub 2019 Apr 6.

Reference Type BACKGROUND
PMID: 30965157 (View on PubMed)

Chatman AB, Hyams SP, Neel JM, Binkley JM, Stratford PW, Schomberg A, Stabler M. The Patient-Specific Functional Scale: measurement properties in patients with knee dysfunction. Phys Ther. 1997 Aug;77(8):820-9. doi: 10.1093/ptj/77.8.820.

Reference Type BACKGROUND
PMID: 9256870 (View on PubMed)

Demers L, Monette M, Descent M, Jutai J, Wolfson C. The Psychosocial Impact of Assistive Devices Scale (PIADS): translation and preliminary psychometric evaluation of a Canadian-French version. Qual Life Res. 2002 Sep;11(6):583-92. doi: 10.1023/a:1016397412708.

Reference Type BACKGROUND
PMID: 12206579 (View on PubMed)

Middleton A, Fritz SL, Lusardi M. Walking speed: the functional vital sign. J Aging Phys Act. 2015 Apr;23(2):314-22. doi: 10.1123/japa.2013-0236. Epub 2014 May 2.

Reference Type BACKGROUND
PMID: 24812254 (View on PubMed)

Probsting E, Kannenberg A, Zacharias B. Safety and walking ability of KAFO users with the C-Brace(R) Orthotronic Mobility System, a new microprocessor stance and swing control orthosis. Prosthet Orthot Int. 2017 Feb;41(1):65-77. doi: 10.1177/0309364616637954. Epub 2016 Jul 10.

Reference Type BACKGROUND
PMID: 27151648 (View on PubMed)

Schmalz T, Probsting E, Auberger R, Siewert G. A functional comparison of conventional knee-ankle-foot orthoses and a microprocessor-controlled leg orthosis system based on biomechanical parameters. Prosthet Orthot Int. 2016 Apr;40(2):277-86. doi: 10.1177/0309364614546524. Epub 2014 Sep 23.

Reference Type BACKGROUND
PMID: 25249381 (View on PubMed)

Filiatrault J, Gauvin L, Fournier M, Parisien M, Robitaille Y, Laforest S, Corriveau H, Richard L. Evidence of the psychometric qualities of a simplified version of the Activities-specific Balance Confidence scale for community-dwelling seniors. Arch Phys Med Rehabil. 2007 May;88(5):664-72. doi: 10.1016/j.apmr.2007.02.003.

Reference Type BACKGROUND
PMID: 17466738 (View on PubMed)

Andrade LF, Ludwig K, Goni JMR, Oppe M, de Pouvourville G. A French Value Set for the EQ-5D-5L. Pharmacoeconomics. 2020 Apr;38(4):413-425. doi: 10.1007/s40273-019-00876-4.

Reference Type BACKGROUND
PMID: 31912325 (View on PubMed)

Other Identifiers

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2022-A00116-37

Identifier Type: OTHER

Identifier Source: secondary_id

BP-11-PT007

Identifier Type: -

Identifier Source: org_study_id

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