Virtual Reality Training Intervention on Cognitive Function and Quality of Life

NCT ID: NCT05329272

Last Updated: 2022-04-14

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-01-31
• Study Completion Date: 2018-12-31

Brief Summary

The present study aimed to investigate the effects of a Virtual Reality cognitive training intervention (VRCTI) on cognitive function changes measured with a cognitive test battery and improvement of quality of life in older adults with cognitive impairment in long-term care facilities. Weekly 1-hour sessions were implemented over 8 weeks targeting sustained and selective attention, memory, cognitive functions, and rule deduction. The passive control group received usual care.

Detailed Description

Objectives: The present study aimed to investigate the effects of a Virtual Reality cognitive training intervention (VRCTI) on cognitive function changes measured with a cognitive test battery and improvement of quality of life in older adults with cognitive impairment in long-term care facilities.

Method: Weekly 1-hour sessions were implemented over 8 weeks targeting sustained and selective attention, memory, cognitive functions, and rule deduction. The VRCTI comprised 12 different tasks distributed in 8 sessions with different difficulty levels. The passive control group received usual care. Older adults were randomly assigned to either VR or control groups. An experimental pre-post design was used. Accuracy, error, and repetition rates were measured throughout each session. Intervention effects were analyzed using a generalized estimating equation model.

Conditions

Virtual Reality; Cognitive Impairment; Quality of Life

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: NONE

Study Groups

The VR group: the Virtual Reality Cognitive Training Intervention (VRCTI)

The VRCTI was developed to improve cognitive function. The intervention was designed that simulated schema of underwater world fish swimming. Each 1-hour session was typically divided into three parts: easy, medium and difficult, each with 4 different tasks, so there are 12 tasks/session in total. In some tasks, the VRCTI also distinguished between the real lure (e.g. a red triangle fish with a half-moon pattern) as well as unrelated lure items (i.e., blue square fish with polka dot pattern and other irrelevant items). The use of hardware elements for this study included visual (head-mounted display \[HMD\] in delivering the VR intervention), audio, and motor equipment.

Group Type: EXPERIMENTAL

Virtual Reality Cognitive Training Intervention (VRCTI)

Intervention Type: OTHER

The VRCTI was developed to improve cognitive function. The intervention was designed that simulated schema of underwater world fish swimming. Each 1-hour session was typically divided into three parts: easy, medium and difficult, each with 4 different tasks, so there are 12 tasks/session in total. In some tasks, the VRCTI also distinguished between the real lure (e.g. a red triangle fish with a half-moon pattern) as well as unrelated lure items (i.e., blue square fish with polka dot pattern and other irrelevant items). The use of hardware elements for this study included visual (head-mounted display \[HMD\] in delivering the VR intervention), audio, and motor equipment.

The control group

The control group received usual care.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Virtual Reality Cognitive Training Intervention (VRCTI)

The VRCTI was developed to improve cognitive function. The intervention was designed that simulated schema of underwater world fish swimming. Each 1-hour session was typically divided into three parts: easy, medium and difficult, each with 4 different tasks, so there are 12 tasks/session in total. In some tasks, the VRCTI also distinguished between the real lure (e.g. a red triangle fish with a half-moon pattern) as well as unrelated lure items (i.e., blue square fish with polka dot pattern and other irrelevant items). The use of hardware elements for this study included visual (head-mounted display \[HMD\] in delivering the VR intervention), audio, and motor equipment.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Aged ≥ 65 years
• Admitted as residents at the study-site institutions (long-term care facilities)
• Mini Mental Status Examination (MMSE) ≥ 13
• Able to communicate sufficiently

Exclusion Criteria

• Open facial wounds
• Problems with a finger, hand, or wrist and/or major visual or auditory impairment, making it difficult to deliver training scheme
• Major neurological or psychiatric conditions that may affect cognition (e.g., stroke, dizziness, schizophrenia)
• Unstable medical conditions
• Were unable to comply with the intervention

• Minimum Eligible Age: 65 Years
• Maximum Eligible Age: 99 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

I-Shou University

OTHER

Sponsor Role: lead

Responsible Party

Mei-Chi Hsu

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Mei-Chi Hsu, Ph.D

Role: PRINCIPAL_INVESTIGATOR

I-Shou University

Locations

I-Shou University

Kaohsiung City, , Taiwan

Countries

Taiwan

Other Identifiers

IShouU-VR

Identifier Type: -

Identifier Source: org_study_id