Blood Loss Measurement Using Electrical Impedance Tomography

NCT ID: NCT05287334

Last Updated: 2022-08-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-07-01

Study Completion Date

2022-12-31

Brief Summary

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The project focuses on the possibility of detecting blood loss using electrical impedance tomography. Based on previous animal experiments, it was found that the bolus of saline significantly affects the signal of chest bioimpedance. It is assumed that blood loss of a similar volume will cause a similar signal change with the opposite trend. The aim of this project is to determine whether there is a significant change in the thoracic electrical impedance tomography signal when blood loss is caused by voluntary blood donation.

Detailed Description

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Electrical impedance tomography is a bedside method of ventilation monitoring. The bioimpedance of the tissue depends, among other things, on its blood content. The area of the chest and especially the lungs is a heavily perfused tissue, which also serves as one of the reservoirs of blood in case of blood loss. It is therefore possible that blood loss will be visible on chest bioimpedance relatively soon.

The study will be performed on voluntary blood donors. Blood loss of 450 mL will be caused by the collection of donated blood. During blood collection at the transfusion department, thoracic bioimpedance will be measured using electrical impedance tomography. The resulting signal change will then be analyzed to determine the possibility of detecting and measuring blood loss using electrical impedance tomography.

Conditions

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Blood Loss

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Single group assignment. Approx 10-15 voluntary blood donors.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Voluntary blood donors

Voluntary blood donors undergoing standard blood donation while measuring electrical impedance of the chest .

Group Type EXPERIMENTAL

Electrical impedance tomography measurement

Intervention Type DEVICE

During standard blood donation, donors' chest bioimpedance will be measured using electrical impedance tomography.

Interventions

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Electrical impedance tomography measurement

During standard blood donation, donors' chest bioimpedance will be measured using electrical impedance tomography.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* voluntary blood donation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Military University Hospital, Prague

OTHER

Sponsor Role collaborator

Czech Technical University in Prague

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vaclav Ort, M.Eng.

Role: PRINCIPAL_INVESTIGATOR

Czech Technical University in Prague, Fac. of Biomedical Engineering

Locations

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Czech Technical University, Faculty of Biomedical Engineering

Kladno, , Czechia

Site Status RECRUITING

Czech technical university in Prague, Facutly of biomedical engineering

Kladno, , Czechia

Site Status RECRUITING

Countries

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Czechia

Central Contacts

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Vaclav Ort, M.Eng.

Role: CONTACT

+420 731 577 649

Facility Contacts

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Karel Roubik, PhD

Role: primary

+420 603 479 901

Vaclav Ort, M.Eng

Role: primary

+420731577649

Other Identifiers

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12229

Identifier Type: -

Identifier Source: org_study_id

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