Rehabilitation of Facial Emotion Recognition in Alzheimer's Disease

NCT ID: NCT05267028

Last Updated: 2023-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

16 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-10

Study Completion Date

2023-03-22

Brief Summary

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EYE-TAR(AD+) is an observational study based on the same design as the princeps EYE-TAR(MA) study, but with a larger number of patients and including an additional evaluation of Facial emotion recognition (based on a more ecological material), in order to reinforce conclusions of the study EYE-TAR(MA) https://doi.org/10.1016/j.npg.2020.08.003.

The main objective is to confirm that facial emotion recognition can be improved in AD using the "Training of Affect Recognition program" (TAR).

The Secondary Objectives are to:

Evaluate the impact of the "Training of Affect Recognition program" (TAR) on oculomotor behavior in a situation of social cognition, on behavioral disorders and on caregiver burden.

Confirm that improvement in facial emotion recognition is related to modification of observation strategies.

Confirm the link between improved recognition of facial emotions, reduced behavioral disorders and caregiver burden.

Detailed Description

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Conditions

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Alzheimer's Dementia (AD) Family Caregivers

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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AD-TAR

AD subjects who take part to Facial Emotion Recognition rehabilitation (TAR)

AD-TAR

Intervention Type OTHER

12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using a rehabilitation program named Training of Affect Recognition (TAR).

AD-Cognitive Stimulation

AD subjects who take part to cognitive stimulation session (12 sessions during 4 weeks)

AD-Cognitive Stimulation

Intervention Type OTHER

12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using classic cognitive stimulation workshops.

Interventions

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AD-TAR

12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using a rehabilitation program named Training of Affect Recognition (TAR).

Intervention Type OTHER

AD-Cognitive Stimulation

12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using classic cognitive stimulation workshops.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male or Female.
* AD diagnosed according to l'IWG-2 (Dubois \& al. 2014) criteria,
* Mini-Mental State (MMS-E) ≥15
* Subject accompanied by a family caregiver and whose participation in a cognitive stimulation workshop was recommended in Memory Centre of the RAINIER Centre (Princesses Grace Hospital - Monaco)
* Written informed consent signed by patient and family caregiver.

Exclusion Criteria

* General anaesthesia within 3 months.
* History of psychiatric and/or neurological disorder (other than the diagnosed neurodegenerative pathology);
* History of alcoholism or drug addiction
* Ophthalmological or neurological problems preventing a video-oculography examination.
* Oculomotor disorders such as "fixation disorders" or "ocular tracking disorders".
* Cognitive disorders of the neurovisual type (visual agnosia, prosopagnosia, visuo-spatial disorder or visuo-perceptual disorder) or aphasia.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Princesse Grace

OTHER

Sponsor Role collaborator

Universite Cote d'Azur

OTHER

Sponsor Role collaborator

Association de Recherche Bibliographique pour les Neurosciences

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sandrine LOUCHART DE LA CHAPELLE, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Mémoire, Centre de Gérontologie Clinique RAINIER III, Princess Grace Hospital, Monaco

Locations

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Centre Mémoire / Centre de Gérontologie Clinique Rainier III / Princess Grace Hospital

Monaco, , Monaco

Site Status

Countries

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Monaco

Other Identifiers

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EYE-TAR(AD+)

Identifier Type: -

Identifier Source: org_study_id

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