Outcome of Discharged HFmrEF Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1693 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-01

Study Completion Date

2021-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aimed to define the independent risk factors related cardiac events (cardiac death or heart failure-related hospitalization) among heart failure with mildly reduced ejection fraction (HFmrEF) patients who discharged from the Xiangtan Central Hospital. Through the long-term follow-up the cardiovascular outcome of patients being discharged from the hospital, the risk factors related to cardiovascular outcome (cardiac death or heart failure-related hospitalization) will be explored to provide clinical evidence to intervene the discharged HFmrEF patients aiming to improve patients outcome in the future clinical practice.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Risk Factors In Heart Failure Patients With Preserved Ejection Fraction

NCT06487468

Heart Failure With Preserved Ejection Fraction

COMPLETED

Study of the Prognosis of Patients With Heart Failure With Preserved Ejection Fraction

NCT05496439

Heart Failure With Preserved Ejection Fraction

COMPLETED

Hospital Register of Decompensated Heart Failure With Preserved Ejection Fraction

NCT06114498

Heart Failure With Preserved Ejection Fraction Obesity, Mild Decompensated Heart Failure

ACTIVE_NOT_RECRUITING

Clinical Study of Active Intervention in High-risk HFpEF Patients

NCT06532019

Heart Failure With Preserved Ejection Fraction

NOT_YET_RECRUITING NA

The Relationship Between Epicardial Fat Tissue and Cardiac Function in HFpEF Patients

NCT05068934

Heart Failure With Preserved Ejection Fraction

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study aimed to define the independent risk factors related cardiac events (cardiac death or heart failure-related hospitalization) among heart failure with mildly reduced ejection fraction (HFmrEF) patients who hospitalized in Xiangtan Central Hospital from January 1, 2015 to August 31, 2020. The patients would be clinically followed-up until August 31, 2021 per clinical visit or telephone call, the risk factors related to cardiovascular outcome (cardiac death or heart failure-related hospitalization) will be explored to provide clinical evidence to intervene the discharged HFmrEF patients aiming to improve patients outcome in the future clinical practice.

The clinical features of hospitalized heart failure with mildly reduced ejection fraction (HFmrEF, EF 41-49%) will be analyzed by retrospectively by reviewing patients medical records, laboratory and clinical imaging examination results during initial hospitalization, clinical outcome of enrolled patients will be obtained through clinical visit and telephone call. The primary endpoint is the composite cardiac events (cardiac death or heart failure related rehospitalization). The secondary endpoint is the all-cause death.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Heart Failure With Mid Range Ejection Fraction

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

HFmrEF Group

HFmrEF (Heart failure with mildly reduced ejection fraction): ESC Guideline heart failure 2021: patients with LVEF 41-49%.

non-cardiac events group versus cardiac events (cardiac death or heart failure-related rehospitalization) group

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Diagnosis: Heart failure with mildly reduced ejection fraction (HFmrEF) Presence of symptoms and/or signs of HF, and a mildly reduced LVEF (41- 49%); Elevated natriuretic peptides (BNP \>35 pg/mL or NT-proBNP \>125 pg/mL); Other evidence of structural heart disease.