Understanding and Treating Heart Failure With Preserved Ejection Fraction: Novel Mechanisms, Diagnostics and Potential Therapeutics
NCT ID: NCT02052804
Last Updated: 2022-05-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
700 participants
OBSERVATIONAL
2009-04-30
2022-05-02
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Characterization of Heart Failure With Preserved Ejection Fraction
NCT03197350
The Use of Advanced Imaging in HFpEF
NCT06905405
Clinical Characteristics and Predictors of Adverse Outcomes in HFpEF
NCT06228807
Classification of Heart Failure With Preserved Ejection Fraction
NCT01030991
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
NCT06517186
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Group 2 Known coronary artery disease
* Group 3 Known heart failure with preserved ejection fraction
* Group 4 Known heart failure with reduced ejection fraction
* Group 5 Healthy age-matched controls
Exclusion Criteria
* Known malignancy with expected survival \<1 year
* Pregnant or recent pregnancy \<6 months
* Recent event (\<2 weeks since Acute Coronary Syndrome, Heart failure or other admission
* Severe mitral or aortic stenosis
18 Years
100 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Alberta
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Justin Ezekowitz
Associate Professor, University of Alberta; Director, Heart Function Clinic- Mazankowski Alberta Heart Institute
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Jason Dyck, PhD
Role: STUDY_DIRECTOR
University of Alberta
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Calgary
Calgary, Alberta, Canada
University of Alberta
Edmonton, Alberta, Canada
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Zordoky BN, Sung MM, Ezekowitz J, Mandal R, Han B, Bjorndahl TC, Bouatra S, Anderson T, Oudit GY, Wishart DS, Dyck JR; Alberta HEART. Metabolomic fingerprint of heart failure with preserved ejection fraction. PLoS One. 2015 May 26;10(5):e0124844. doi: 10.1371/journal.pone.0124844. eCollection 2015.
Ezekowitz JA, Becher H, Belenkie I, Clark AM, Duff HJ, Friedrich MG, Haykowsky MJ, Howlett JG, Kassiri Z, Kaul P, Kim DH, Knudtson ML, Light PE, Lopaschuk GD, McAlister FA, Noga ML, Oudit GY, Paterson DI, Quan H, Schulz R, Thompson RB, Weeks SG, Anderson TJ, Dyck JR. The Alberta Heart Failure Etiology and Analysis Research Team (HEART) study. BMC Cardiovasc Disord. 2014 Jul 25;14:91. doi: 10.1186/1471-2261-14-91.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
AHFMRITG200801018
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.