Effects of Body Position and Recruiting Maneuver on Lung Aeration Assessed Through Ultrasound in Patients Intubated for Acute Respiratory Failure Related to Novel Coronavirus 19 Disease

NCT ID: NCT05209477

Last Updated: 2024-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-01

Study Completion Date

2022-05-31

Brief Summary

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Second analysis of data prospectively collected during an investigation assessing the clinical characteristics of patients admitted for hypoxemic acute respiratory failure (hARF) related to novel coronavirus 19 disease (COVID-19). In particular, the primary aim of the present analysis is to assess the effects of recruiting maneuver and prone positioning on lung aeration evaluated through lung ultrasound in patients undergoing invasive mechanical ventilation

Detailed Description

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Conditions

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Acute Respiratory Failure

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Lung ultrasound

n patients undergoing invasive mechanical ventilation with an arterial oxygen tension on inspired oxygen fraction ratio \< 200 mmHg requiring recruitment maneuver and prone positioning as a rescue therapy, lung aeration will be evaluated at:

baseline, in supine position under protective ventilation after two minute of recruitment maneuver in pressure controlled ventilation at 1 hour following prone positioning application

Group Type OTHER

lung ultrasound assessment

Intervention Type OTHER

In patients undergoing invasive mechanical ventilation with an arterial oxygen tension on inspired oxygen fraction ratio \< 200 mmHg requiring recruitment maneuver and prone positioning as a rescue therapy, lung aeration will be evaluated at:

1. baseline, in supine position under protective ventilation
2. after two minute of recruitment maneuver in pressure controlled ventilation
3. at 1 hour following prone positioning application

Interventions

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lung ultrasound assessment

In patients undergoing invasive mechanical ventilation with an arterial oxygen tension on inspired oxygen fraction ratio \< 200 mmHg requiring recruitment maneuver and prone positioning as a rescue therapy, lung aeration will be evaluated at:

1. baseline, in supine position under protective ventilation
2. after two minute of recruitment maneuver in pressure controlled ventilation
3. at 1 hour following prone positioning application

Intervention Type OTHER

Eligibility Criteria

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Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Azienda Ospedaliera di Perugia

OTHER

Sponsor Role lead

Responsible Party

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Prof Gianmaria Cammarota

Prof Gianmaria Cammarota md, phd

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Università degli Studi di Perugia

Perugia, Umbria, Italy, Italy

Site Status

Countries

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Italy

Other Identifiers

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12/21

Identifier Type: -

Identifier Source: org_study_id

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