HFNC and Prone Positioning in Awake Patients With Severe COVID-19

NCT ID: NCT04982341

Last Updated: 2021-07-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-02

Study Completion Date

2021-03-03

Brief Summary

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The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.

Detailed Description

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The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.

All patients with ARF related to Covid-19 and admitted to the ICU are turned in prone position whenever tolerated, while receiving oxygenation with HFNC.

Outcomes of interest are the rate of success or failure (defined as the need for intubation and mechanical ventilation)

Conditions

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Hypoxemic Respiratory Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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HFNC/prone

awake patients with COVID-19 and severe acute respiratory failure receiving HFNC in prone position

prone position

Intervention Type PROCEDURE

patients are returned from prone to supine position while receiving oxygenation through HFNC

Interventions

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prone position

patients are returned from prone to supine position while receiving oxygenation through HFNC

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* aged ≥18 years, admitted to the medical ICU for confirmed Covid-19 and acute hypoxemic respiratory failure

Exclusion Criteria

* patients already intubated at admission or those requiring immediate intubation
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hôpital Universitaire Fattouma Bourguiba

OTHER

Sponsor Role lead

Responsible Party

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Fekri Abroug

Professor Head of the ICU

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lamia Besbes, Prof

Role: STUDY_CHAIR

CPPRB

Locations

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CHU F.Bourguiba

Monastir, , Tunisia

Site Status

Countries

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Tunisia

Other Identifiers

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FattoumaBourguiba_HFNC_Prone

Identifier Type: -

Identifier Source: org_study_id

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