Visual Attention Span Mobilisation for Dyslexia

NCT ID: NCT05201235

Last Updated: 2024-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-17

Study Completion Date

2023-07-05

Brief Summary

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The aim of the study is to evaluate the efficiency of the medical device MAEVAD in improving the reading skills of children with dyslexia.

Detailed Description

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MAEVAD is a digital therapy specifically designed to improve the visual attention (VA) span of children with dyslexia. Dyslexia is characterized by a specific and significant impairment in reading and/or writing production and spelling. Some profiles of children with dyslexia show a deficit in VA span, characterized by a decrease in the number of distinct visual elements that can be processed simultaneously. VA span plays a critical role in the acquisition of reading skills and specific knowledge of word spelling. Brain regions involved in visual-attentional skills are under-activated in dyslexic children with VA deficits and can be reactivated following specific and intensive VA span training.

In this study 150 children with dyslexia will be randomized in tow groups. On the first group children will be trained first with MAEVAD then with a control training that does not stimulate the VA span. On contrary, on the second group children will first perform the control training and then MAEVAD.

For each intervention the sessions will lasts 15 minutes. 5 sessions are planned per weeks for 6 weeks.

Conditions

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Dyslexia Visual Attention Span Deficit

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

On the first group children will be trained first with MAEVAD then with a control training that does not stimulate the VA span. On contrary, on the second group children will first perform the control training and then MAEVAD.

For each intervention the sessions will lasts 15 minutes. 5 sessions are planned per weeks for 6 weeks.
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
The training will be performed at home. The investigators/evaluators will send a download link of the therapy to the patient's parents without knowing which therapy it corresponds to.

Study Groups

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MAEVAD - DeCaLigne

The experimental group will first receive MAEVAD then the control therapy

Group Type EXPERIMENTAL

MAEVAD

Intervention Type DEVICE

MAEVAD is a training device which aims to improve VA span as a prerequisite for learning to read. By increasing the number of distinct visual elements that can be processed simultaneously during fixation, MAEVAD is intended to improve the reading (accuracy and fluency) and spelling (lexical) performance of dyslexics who have a VA span deficit. MAEVAD is designed to be used in total autonomy by dyslexic children with a VA span disorder. The therapy takes place over 6 weeks with 5 sessions of 15 minutes per week. In order to improve compliance, the therapy has been integrated into "le Royaume d'Adelia", a serious game where the child will be able to collect materials at the end of each session that will allow him to create objects to customise a character.

DeCaLigne - MAEVAD

The control group will first receive the control therapy then MAEVAD

Group Type PLACEBO_COMPARATOR

DeCaLigne

Intervention Type DEVICE

DéCaLigne is an intervention programme for the discovery of calculation with the number line. The objectives are to improve numerical representations in the form of a number line and to improve addition and subtraction skills. The overall principle is to move numbers or calculation results on a number line. This training does not stimulate VA span or the phonological dimensions involved in reading. This therapy is being adapted to be used in total autonomy at home and to correspond to the MAEVAD therapy in duration (5 sessions of 15 minutes per week for 6 weeks). It has also been integrated into the "royaume d'Adelia" in order to control the motivational effect of the serious game.

Interventions

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MAEVAD

MAEVAD is a training device which aims to improve VA span as a prerequisite for learning to read. By increasing the number of distinct visual elements that can be processed simultaneously during fixation, MAEVAD is intended to improve the reading (accuracy and fluency) and spelling (lexical) performance of dyslexics who have a VA span deficit. MAEVAD is designed to be used in total autonomy by dyslexic children with a VA span disorder. The therapy takes place over 6 weeks with 5 sessions of 15 minutes per week. In order to improve compliance, the therapy has been integrated into "le Royaume d'Adelia", a serious game where the child will be able to collect materials at the end of each session that will allow him to create objects to customise a character.

Intervention Type DEVICE

DeCaLigne

DéCaLigne is an intervention programme for the discovery of calculation with the number line. The objectives are to improve numerical representations in the form of a number line and to improve addition and subtraction skills. The overall principle is to move numbers or calculation results on a number line. This training does not stimulate VA span or the phonological dimensions involved in reading. This therapy is being adapted to be used in total autonomy at home and to correspond to the MAEVAD therapy in duration (5 sessions of 15 minutes per week for 6 weeks). It has also been integrated into the "royaume d'Adelia" in order to control the motivational effect of the serious game.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* School children from CE2 to CM2, aged 8 to 11 years
* Dyslexic children with a VA span deficit (composite visual-attention span below the fifteenth percentile and a letter threshold above or equal to the twentieth percentile with the - - - Evadys(c) battery)
* Established diagnosis of Dyslexia
* Children whose parents/legal guardians have signed informed consent and agree to participate in the study
* Children whose first language is French or who have been educated in French since kindergarten
* Raven's Progressive Matrices score above the 20th percentile or a WISC IV or V Verbal Comprehension Index or WISC IV or V Perceptual/Fluid Reasoning Index above 85 or documented/objectifiable absence of intellectual deficit
* Child with access to a computer
* Normal or corrected vision and audition

Exclusion Criteria

* Attention deficit hyperactivity disorder,dysphasia, dyspraxia, Autism Spectrum Disorder
* Neurological disorders
* Children who have missed 3 months or more of school in the current or previous year (excluding lockdown)
* Children not affiliated to a social security scheme
Minimum Eligible Age

8 Years

Maximum Eligible Age

11 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Humans Matter

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mélodie FOUILLEN, PhD

Role: STUDY_CHAIR

Humans Matter

Locations

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MARTINELLI Karen

Ajaccio, , France

Site Status

BERARD Marine

Albertville, , France

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CARCEY-CADET Elise

Albertville, , France

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KOUASSI-PUJOL Marie

Albi, , France

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CLAVIER-MARCOUX Laetitia

Antibes, , France

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BOCCOGNANI Jordane

Argences en Aubrac, , France

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CHAUVET Clémence

Arles, , France

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CHABERT Claire

Bagnères-de-Bigorre, , France

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SCHMITT Véronique

Biganos, , France

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CRABÉ Marion

Billère, , France

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BIRAN Sandrine

Bordes, , France

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VALLERY Théoline

Brest, , France

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LADOUL Marine

Brive-la-Gaillarde, , France

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COURANT Sabrina

Cabasse, , France

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CONTESTI Véronique

Champagne-au-Mont-d'Or, , France

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MINIAC-FOURNIER Stéphanie

Château-Gontier, , France

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CASTERES Catherine

Digoin, , France

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PASQUIER Amélie

Fay-de-Bretagne, , France

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LEGENDRE Laure

Fontenay-sous-Bois, , France

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FORTIER Anne

Garches, , France

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BLANC Emilie

Givors, , France

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KRAYEM Mona

Guichainville, , France

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RIZK Joumana

Guichainville, , France

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SHAW PERRIN Anne-Sophie

Irigny, , France

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DE MUYNCK Solène

Lamballe, , France

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CADALEN Hélène

Lanmeur, , France

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VOLUET FROMENT Adeline

Le Chesnay, , France

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BERNARD-DENIS Fabienne

Le Havre, , France

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TERRASSON Cécile

Le Touquet-Paris-Plage, , France

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CALAIS Cécile

Liancourt, , France

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Britt

Lux, , France

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GOBÉ Valérie

Machecoul, , France

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JORDANIS Mélanie

Marignier, , France

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VERLOT-MORY Ludivine

Meuilley, , France

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MAZERAN Anne-Cécile

Miribel, , France

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KIS Nathalie

Montigny-le-Bretonneux, , France

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EMERIAU Mathilde

Nantes, , France

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LHUILLIER Françoise

Neufchâteau, , France

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LEJOSNE Julie

Paimpol, , France

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BRESSON Raphaëlle

Plaisir, , France

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BERTHELOT Florence

Plérin, , France

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BERTHOLOM Anne-Marine

Ploudalmézeau, , France

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ZIMMERMAN Amélie

Remoulins, , France

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CAMUS-BRUNEAU Anne

Rezé, , France

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KOCHEL Jeanne-Marie

Saint-Germain-en-Laye, , France

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VIERLING Pauline

Saint-Leu, , France

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LECLERC LE COADOU Rozenn

Saint-Lô, , France

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NADAUD Stéphanie

Saint-Nom-la-Bretêche, , France

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REVERSE Christelle

Saint-Péray, , France

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DESCENDRE Myriam

Saint-Quentin, , France

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RAYNAUD LEGROS Caroline

Sainte-Anne, , France

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AÏT LEMKADEM Mimouna

Sartrouville, , France

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FRITSCH Colombine

Schiltigheim, , France

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CARRIQUE Pascale

Tourrettes, , France

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KALCK Christine

Vendenheim, , France

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Countries

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France

Other Identifiers

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2021-A01457-34

Identifier Type: -

Identifier Source: org_study_id

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