Clinical Assessment of Essential Remote Monitoring Functions in Pacemakers

NCT ID: NCT05165095

Last Updated: 2024-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

206 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-25

Study Completion Date

2027-07-31

Brief Summary

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The purpose of the clinical investigation is to document the safety and the performances of the remote monitoring functions of the ALIZEA, BOREA and CELEA pacemakers, i.e. the RAAT, the RVAT and the remote alerts.

Detailed Description

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All patients will be included just after implantation and will then be followed during 48 months after inclusion.

At each on-site or remote follow-up visit (1 to 3 months, 6, 12, 24 and 48 months), performances of the remote monitoring functions and the cardiac pacing system itself will be measured, and safety will be monitored during the whole clinical investigation duration.

Conditions

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Bradycardia Remote Monitoring

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Pacemaker implantation

De novo implantation, device upgrade to dual chamber or device replacement

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Patient implanted according to the most recent guidelines from the ESC, for 20 days or less (de novo implantation, device upgrade to dual chamber or device replacement)
2. Patient implanted with an ALIZEA, BOREA or CELEA dual chamber pacemaker from MicroPort CRM
3. Patient implanted with any active or passive CE marked bipolar RA lead, and any active or passive CE marked bipolar RV lead
4. Patient's pacemaker with the remote monitoring functions (i.e. the RAAT, the RVAT and the remote alerts) accepted by the patient and planned to be activated
5. Patient reviewed, signed and dated the ICF

Exclusion Criteria

1. Patient with an elevated RV pacing threshold (strictly above 2.0 V for a pulse width of 0.5 ms or below)
2. Patient with permanent AF
3. Patient already enrolled in another clinical investigation that could confound the results of this clinical investigation (e.g., clinical investigations involving intra-cardiac device)
4. Patient implanted despite a contraindication for cardiac pacing system implantation (i.e. patient implanted with a defibrillator, patient contraindicated for a single dose of 310 μg of dexamethasone sodium phosphate, patient implanted with a tricuspid replacement heart valve or with a significant tricuspid valve disease that may lead to future replacement heart valve surgery)
5. Minor age patient (i.e. under 18 years of age)
6. Incapacitated patient, under guardianship, kept in detention, refusing to cooperate or not able to understand the purpose of this clinical investigation
7. Patient unavailable for the follow-up visits scheduled
8. Non-menopausal women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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MicroPort CRM

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Universitätsklinikum Krems

Krems, , Austria

Site Status RECRUITING

Allgemeines Krankenhaus Wien

Vienna, , Austria

Site Status RECRUITING

Clinique Saint Joseph

Arlon, , Belgium

Site Status RECRUITING

CHU Bordeaux

Bordeaux, , France

Site Status RECRUITING

CH Chartres

Le Coudray, , France

Site Status RECRUITING

CHU Hôpital de la Timone

Marseille, , France

Site Status RECRUITING

CHU Nantes

Nantes, , France

Site Status RECRUITING

Clinique Pasteur Toulouse

Toulouse, , France

Site Status RECRUITING

CH Valence

Valence, , France

Site Status RECRUITING

Cardiologicum Hamburg

Hamburg, , Germany

Site Status RECRUITING

Cardiologicum Pirna

Pirna, , Germany

Site Status RECRUITING

Kardiologische Praxis Dr. Trautwein & Dr. Placke

Rostock, , Germany

Site Status RECRUITING

Ziekenhuis VieCuri Venlo

Venlo, , Netherlands

Site Status RECRUITING

Hospital Professor Doutor Fernando Fonseca

Amadora, , Portugal

Site Status RECRUITING

Hospital Arquitecto Marcide

Ferrol, , Spain

Site Status RECRUITING

Hospital Universitario Puerta de Hierro

Majadahonda, , Spain

Site Status RECRUITING

Basildon University Hospital

Basildon, , United Kingdom

Site Status NOT_YET_RECRUITING

Kingston Hospital

London, , United Kingdom

Site Status RECRUITING

Southend University Hospital

Westcliff-on-Sea, , United Kingdom

Site Status RECRUITING

Countries

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Austria Belgium France Germany Netherlands Portugal Spain United Kingdom

Central Contacts

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Antoine Guihard

Role: CONTACT

+33 1 46 01 33 20

Facility Contacts

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Daniel Gerger

Role: primary

Marianne Gwechenberger

Role: primary

Georges Mairesse

Role: primary

Marc Strik

Role: primary

Hervé Gorka

Role: primary

Jean-Claude Deharo

Role: primary

Vincent Probst

Role: primary

Romain Cassagneau

Role: primary

Alexandre Guignier

Role: primary

Martin Bergmann

Role: primary

Christoph Axthelm

Role: primary

Jens Placke

Role: primary

Ronald Hazeleger

Role: primary

Francisco Madeira

Role: primary

Fernando Garcia López

Role: primary

Ignacio Fernandez-Lozano

Role: primary

Neil Srinivasan

Role: primary

Simon Pearse

Role: primary

Neil Srinivasan

Role: primary

Other Identifiers

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IPBI01 - CALLIOPE

Identifier Type: -

Identifier Source: org_study_id

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