Continuation of Aspirin Before Isolated Heart Valve Surgery

NCT ID: NCT05151796

Last Updated: 2021-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-01

Study Completion Date

2021-12-01

Brief Summary

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Whether or not continuing aspirin up to de day before surgery increases the risk of bleeding and/or prevents thrombo-embolic complications remains debated. The investigators retrospectively investigated the whether continuing aspirine within 5 days of isolated heart valve surgery increased the risk of bleeding.

Detailed Description

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Conditions

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Isolated Heart Valve Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Aspirin continued within 5 days before surgery

Aspirin

Intervention Type DRUG

Daily aspirin intake for cardiovascular prevention

Aspirin discontinued more than 5 days before surgery

No interventions assigned to this group

Interventions

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Aspirin

Daily aspirin intake for cardiovascular prevention

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Isolated heart valve surgery

Exclusion Criteria

* Antiplatelet agent other than aspirin or anticoagulant not discontinued preoperatively
* Emergent or salvage surgery
* Surgery for endocarditis
* Use of NSAIDs within 48 hours before surgery
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Liege

OTHER

Sponsor Role lead

Responsible Party

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Jean François Brichant

Professor of Anesthesia

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Vincent Bonhomme, MD, PhD

Role: STUDY_CHAIR

CHU of Liège

Locations

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CHU of Liege

Liège, Liege, Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Gregory Hans, MD

Role: CONTACT

Email: [email protected]

Facility Contacts

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Gregory Hans, MD, PhD

Role: primary

Alan Houben, MD

Role: backup

References

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Houben AM, Crepy M, Senard M, Bonhomme V, Tchana-Sato V, Hans G. Preoperative continuation of aspirin before isolated heart valve surgery and postoperative bleeding and transfusion: a single-center retrospective study. Acta Chir Belg. 2024 Aug;124(4):274-280. doi: 10.1080/00015458.2023.2298097. Epub 2023 Dec 26.

Reference Type DERIVED
PMID: 38146908 (View on PubMed)

Other Identifiers

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ulganescardio_aspirine

Identifier Type: -

Identifier Source: org_study_id