MRI & QST Analysis in Trigeminal Neuralgia and Persistent Idiopathic Facial Pain

NCT ID: NCT05147454

Last Updated: 2024-07-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-11

Study Completion Date

2024-07-17

Brief Summary

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Patients with a definite diagnosis of classical TGN and PIFP will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing. Clinical measures and sensory profiles will be correlated with MRI measures.

Detailed Description

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Patients with a definite diagnosis of classical TGN and PIFP (according to the 2020 ICOP Classification) will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing. Clinical measures and sensory profiles will be correlated with the presence and the geometry of neurovascular compression at MRI. Moreover quantitative structural neuroimaging analysis, such as trigeminal root volume, will be performed in each patient and correlated with clinical and QST data.

Conditions

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Facial Pain

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Study Groups

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Trigeminal Neuralgia

Patients with a definite diagnosis of Classical or Idiopathic Trigeminal Neuralgia

Quantitative Sensory Testing

Intervention Type OTHER

Non-invasive assessment of Sensory Profile

Persistent Idiopathic Facial Pain

Patients with a definite diagnosis of Persistent Idiopathic Facial Pain

Quantitative Sensory Testing

Intervention Type OTHER

Non-invasive assessment of Sensory Profile

Interventions

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Quantitative Sensory Testing

Non-invasive assessment of Sensory Profile

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Definite diagnosis of Classical or Idiopathic Trigeminal Neuralgia or Persistent Idiopathic Facial Pain according to the latest ICOP 2020 Criteria
* Naive to any surgical procedures

Exclusion Criteria

* Any major chronic painful or other neurological disease
* Diagnosis of Secondary Trigeminal Neuralgia
* Diagnosis of other facial pain syndromes
* Cognitive disturbances
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Walton Centre NHS Foundation Trust

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Walton Centre NHS Foundation Trust

Liverpool, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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RG447-21

Identifier Type: -

Identifier Source: org_study_id

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