Sphenopalatine Ganglion Block and Pain Management in Neurosurgery
NCT ID: NCT05136625
Last Updated: 2021-11-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
84 participants
INTERVENTIONAL
2021-02-01
2024-06-30
Brief Summary
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Sphenopalatine ganglion block has been successfully used in patients with chronic or acute headache, facial pain and for transsphenoidal pituitary and endoscopic sinus surgeries.
There are evidences that sphenopalatine ganglion block reduces vegetative responses to skull pin closure.
This study aim to investigate feasibility and efficacy of sphenopalatine ganglion block in reducing pain after a neurosurgical supratentorial craniotomy.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Control
Troncular scalp blockade (Levobupivacaine 7,5%) Local site infiltration (Mepivacaine)
Standard Preparation
Troncular scalp blockade. Local site infiltration
Treatment
Troncular scalp blockade (Levobupivacaine 7,5%) Local site infiltration (Mepivacaine) Transnasal sphenopalatine ganglion block (Levobupivacaine 7,5%)
Sphenopalatine ganglion block
A cotton swab soaked in levobupivacaine 7,5% in inserted into the nose to block sphenopalatine ganglion, with the classic technique previously described
Standard Preparation
Troncular scalp blockade. Local site infiltration
Interventions
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Sphenopalatine ganglion block
A cotton swab soaked in levobupivacaine 7,5% in inserted into the nose to block sphenopalatine ganglion, with the classic technique previously described
Standard Preparation
Troncular scalp blockade. Local site infiltration
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* drug assumption: pain-killers (chronic), antiepileptic
18 Years
ALL
No
Sponsors
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University Hospital of Ferrara
OTHER
Responsible Party
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Principal Investigators
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Pasquale De Bonis, MD PhD
Role: STUDY_CHAIR
Università degli Studi di Ferrara
Locations
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Sant'Anna Hospital
Ferrara, Emilia-Romagna, Italy
Countries
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Central Contacts
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Facility Contacts
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Alba Scerrati, MD
Role: primary
References
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Sir E, Eksert S. Morphological Description and Clinical Implication of Sphenopalatine Foramen for Accurate Transnasal Sphenopalatine Ganglion Block: An Anatomical Study. Medeni Med J. 2019;34(3):239-243. doi: 10.5222/MMJ.2019.20586. Epub 2019 Sep 27.
Padhy N, Moningi S, Kulkarni DK, Alugolu R, Inturi S, Ramachandran G. Sphenopalatine ganglion block: Intranasal transmucosal approach for anterior scalp blockade - A prospective randomized comparative study. J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):207-212. doi: 10.4103/joacp.JOACP_249_18. Epub 2020 Jun 15.
Crespi J, Bratbak D, Dodick D, Matharu M, Jamtoy KA, Aschehoug I, Tronvik E. Measurement and implications of the distance between the sphenopalatine ganglion and nasal mucosa: a neuroimaging study. J Headache Pain. 2018 Feb 13;19(1):14. doi: 10.1186/s10194-018-0843-5.
Elahi F, Ho KW. Successful Management of Refractory Headache and Facial Pain due to Cavernous Sinus Meningioma with Sphenopalatine Ganglion Radiofrequency. Case Rep Neurol Med. 2014;2014:923516. doi: 10.1155/2014/923516. Epub 2014 Sep 29.
Mantovani G, Sgarbanti L, Indaimo A, Cavallo MA, De Bonis P, Flacco ME, Scerrati A. Effects of a sphenopalatine ganglion block on postcraniotomy pain management: a randomized, double-blind, clinical trial. Neurosurg Focus. 2023 Dec;55(6):E13. doi: 10.3171/2023.9.FOCUS23549.
Other Identifiers
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553/2021/Sper/AOUFe
Identifier Type: -
Identifier Source: org_study_id