Genetic Study of Amyotrophic Lateral Sclerosis in Norway

NCT ID: NCT05119387

Last Updated: 2025-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-08-01

Study Completion Date

2035-12-31

Brief Summary

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The purpose of this study is to explore the genetic causes relevant for ALS development in Norway.

Detailed Description

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After being informed about the study and potential risks, all patients giving written informed consent will be asked to complete a small questionnaire regarding family history and have a blood sample withdrawn. Blood samples, questionnaires, clinical information and signed consent is send to Department of Medical Genetics, Telemark Hospital Trust were the genetic analysis is performed successively throughout the recruitment period. Patients can choose to have their genetic results returned in a diagnostic setting.

Conditions

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Amyotrophic Lateral Sclerosis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Individuals diagnosed with ALS

Individuals diagnosed with ALS that are being followed through the Norwegian health-care system. ALS patients ( probable or definite per El-Escorial criteria)

Observation

Intervention Type OTHER

Observation of genetic characteristics

Interventions

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Observation

Observation of genetic characteristics

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Probable or definite ALS
* Eligible to consent

Exclusion Criteria

\- not competent to give consent
Minimum Eligible Age

16 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ALS Norge

UNKNOWN

Sponsor Role collaborator

Helse Sor-Ost

OTHER_GOV

Sponsor Role collaborator

Sykehuset Telemark

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Helle Høyer

Role: PRINCIPAL_INVESTIGATOR

Telemark Hospital Trust, Norway

Locations

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Haukeland University Hospital, Department of Neurology

Bergen, , Norway

Site Status RECRUITING

Nordland Hospital Trust, Department of Neurology

Bodø, , Norway

Site Status RECRUITING

Vestre Viken Hospital Trust, Department of Neurology

Drammen, , Norway

Site Status RECRUITING

Førde Hospital Trust, Department of Neurology

Førde, , Norway

Site Status RECRUITING

Østfold Hospital Trust, Department of Neurology

Grålum, , Norway

Site Status RECRUITING

Fonna Hospital Trust, Department of Neurology

Haugesund, , Norway

Site Status RECRUITING

Sørlandet Hospital Trust, Department of Neurology

Kristiansand, , Norway

Site Status RECRUITING

Innlandet Hospital Trust, Department of Neurology

Lillehammer, , Norway

Site Status RECRUITING

Akershus University Hospital, Department of Neurology

Lørenskog, , Norway

Site Status RECRUITING

Møre and Romsdal Hospital Trust, Department of Neurology

Molde, , Norway

Site Status RECRUITING

Nord-Trøndelag Hospital Trust, Department of Neurology

Namsos, , Norway

Site Status RECRUITING

Oslo University Hospital, Department of Neurology

Oslo, , Norway

Site Status RECRUITING

Telemark Hospital, Department of Neurology

Skien, , Norway

Site Status RECRUITING

Stavanger University Hospital, Department of Neurology

Stavanger, , Norway

Site Status RECRUITING

University hospital of North Norway, Department of Neurology

Tromsø, , Norway

Site Status RECRUITING

St. Olavs Hospital, Department of Neurology

Trondheim, , Norway

Site Status RECRUITING

Vestfold Hospital Trust, Department of Neurology

Tønsberg, , Norway

Site Status RECRUITING

Countries

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Norway

Central Contacts

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Helle Høyer

Role: CONTACT

35003146 ext. 0047

Facility Contacts

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Ole-Bjørn Tysnes

Role: primary

Karl Bjørnar Alstadhaug

Role: primary

Ingrid Kristine Bjørnå

Role: primary

Elin Seim

Role: primary

Erika Hallerstig

Role: primary

004769865000

Ineke HogenEsch

Role: primary

Unn Ljøstad

Role: primary

Grethe Kleveland

Role: primary

Trygve Holmøy

Role: primary

Åse Hagen Morsund

Role: primary

Anna Grav

Role: primary

Angelina Maniaol

Role: primary

Heidi Flemmen

Role: primary

Katrin Schlüter

Role: primary

Agnethe Eltoft

Role: primary

Gudveig Lunde Toverud

Role: backup

Geir Bråthen

Role: primary

Natasha Demic

Role: primary

Other Identifiers

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2018/1916

Identifier Type: -

Identifier Source: org_study_id

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