Genetic Origin of Lipid Disorders

NCT ID: NCT00277121

Last Updated: 2006-01-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Study Classification

OBSERVATIONAL

Study Start Date

2006-01-31

Brief Summary

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Several lipid disorders are without known genetic origin. The scope of this project is to sequence genes superior involved in lipid and carbohydrate metabolism in patients with severe lipid disorders. The resulting mutations will be tested in suitable in vitro systems to detect their part in development of the specific disease.

Detailed Description

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See "brief summary" above.

Conditions

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Lipid Disorder

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* proven written informed consent prior to recruitment
* male or female
* 18-55 years old
* patients with severe lipid disorders
* fasting plasma cholesterol, triglyceride or glucose, blood pressure or waist circumference/BMI out of normal range

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

54 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Lipid Clinic, The National Hospital, Oslo, Norway

UNKNOWN

Sponsor Role collaborator

Research Institute of Internal Medicine, The National Hospital, Oslo, Norway

UNKNOWN

Sponsor Role collaborator

Ullevaal University Hospital

OTHER

Sponsor Role collaborator

Norwegian Institute of Public Health

OTHER_GOV

Sponsor Role collaborator

Hormone Laboratory, Aker University Hospital, Oslo, Norway

OTHER

Sponsor Role collaborator

CIGENE, Agricultural University of Norway, Aas, Norway

OTHER

Sponsor Role collaborator

University of Oslo

OTHER

Sponsor Role lead

Principal Investigators

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Hilde I Nebb, PhD

Role: STUDY_CHAIR

Department of Nutrition, University of Oslo

Karianne Solaas, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Nutrition, University of Oslo

Monica H Carlsen

Role: PRINCIPAL_INVESTIGATOR

Department of Nutrition, University of Oslo

Leiv Ose, Dr med

Role: PRINCIPAL_INVESTIGATOR

Lipid Clinic, The National Hospital

Marit S Nenseter, PhD

Role: PRINCIPAL_INVESTIGATOR

Research Institute of Internal Medicine, The National Hospital

Kirsten Holven, PhD

Role: PRINCIPAL_INVESTIGATOR

Research Institute of Internal Medicine, The National Hospital

Bente Halvorsen, PhD

Role: PRINCIPAL_INVESTIGATOR

Research Institute of Internal Medicine, The National Hospital

Serena Tonstad, Dr med

Role: PRINCIPAL_INVESTIGATOR

Department of Preventive Medicine, Ullevål university hospital

Håkon Gjessing, PhD

Role: PRINCIPAL_INVESTIGATOR

Norwegian Institute of Public Health

Per Thorsby, Dr med

Role: PRINCIPAL_INVESTIGATOR

Hormone laboratory, Aker university hospital

Sigbjørn Lien, PhD

Role: PRINCIPAL_INVESTIGATOR

Agricultural university of Norway

Paul Berg, PhD

Role: PRINCIPAL_INVESTIGATOR

Agricultural university of Norway

Kjetil Retterstøl, Dr med

Role: PRINCIPAL_INVESTIGATOR

Lipid Clinic, The National Hospital

Locations

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Department of Nutrition, University of Oslo

Oslo, , Norway

Site Status

Countries

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Norway

Central Contacts

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Hilde Irene Nebb, PhD

Role: CONTACT

+47-22851510

Kjetil Retterstøl, Dr Med

Role: CONTACT

+47-23075603

Other Identifiers

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02/4746 (SHdir)

Identifier Type: -

Identifier Source: secondary_id

10163 (NSD)

Identifier Type: -

Identifier Source: secondary_id

S-03150 (REK)

Identifier Type: -

Identifier Source: org_study_id