Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
39 participants
OBSERVATIONAL
2020-01-01
2021-02-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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ICU patients diagnosed with sepsis or septic shock
compare the laboratory and clinical results of cytokine hemadsorption as an immunomodulation therapy in ICU patients diagnosed with sepsis or septic shock.
cytokine hemadsorption
the laboratory and clinical results of cytokine hemadsorption as an immunomodulation therapy in ICU patients diagnosed with sepsis or septic shock.
Interventions
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cytokine hemadsorption
the laboratory and clinical results of cytokine hemadsorption as an immunomodulation therapy in ICU patients diagnosed with sepsis or septic shock.
Eligibility Criteria
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Inclusion Criteria
* detection of gram-negative bacterial agent in blood or sputum culture.
* patients who had the shock symptoms such as hypotension, tachycardia or fever during the course of sepsis.
Exclusion Criteria
* diagnosed with cardiac failure at stage 4 or renal failure at stage 4 or hepatic liver failure at stage 4
* cancer at the end stage or admitted with acute coronary syndrome.
18 Years
100 Years
ALL
No
Sponsors
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Biruni University
OTHER
Responsible Party
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IKUPELI
investigator
Locations
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Ilke Kupeli
Istanbul, , Turkey (Türkiye)
Countries
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References
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Bahar I, Oksuz H, Senoglu N, Demirkiran H, Aydogan M, Tomak Y, Comez M, Bayrakci S, Gonullu E, Berktas M. Compliance With the Surviving Sepsis Campaign Bundle: A Multicenter Study From Turkey. Cureus. 2021 May 12;13(5):e14989. doi: 10.7759/cureus.14989.
Houschyar KS, Pyles MN, Rein S, Nietzschmann I, Duscher D, Maan ZN, Weissenberg K, Philipps HM, Strauss C, Reichelt B, Siemers F. Continuous hemoadsorption with a cytokine adsorber during sepsis - a review of the literature. Int J Artif Organs. 2017 May 29;40(5):205-211. doi: 10.5301/ijao.5000591. Epub 2017 May 19.
Ye Q, Wang B, Mao J. The pathogenesis and treatment of the ;Cytokine Storm' in COVID-19. J Infect. 2020 Jun;80(6):607-613. doi: 10.1016/j.jinf.2020.03.037. Epub 2020 Apr 10.
Bonavia A, Groff A, Karamchandani K, Singbartl K. Clinical Utility of Extracorporeal Cytokine Hemoadsorption Therapy: A Literature Review. Blood Purif. 2018;46(4):337-349. doi: 10.1159/000492379. Epub 2018 Sep 3.
Other Identifiers
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BIRUNI 2
Identifier Type: -
Identifier Source: org_study_id
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