Evaluation of the Clinical Relationship Between Procalcitonin Level and Bacteremia Agent in Intensive Care Unit Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1529 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-15

Study Completion Date

2025-10-19

Brief Summary

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In intensive care units, sepsis, which can be defined as bacteremia and the irregular and uncontrolled inflammatory response to it, is one of the most important causes of mortality. Early recognition of sepsis and appropriate antibiotic use for the causative agent is one of the most important steps in the fight against sepsis. Procalcitonin (PCT) is a calcitonin precursor peptide and has been reported to predict bacteremia early. While the PCT concentration level is negligible in healthy individuals, it has been shown to increase especially in bacterial infections, sepsis, trauma and burns. In our study, our aim is to determine whether there is a relationship between serum PCT concentration levels taken within 24 hours according to the time of the sample taken for blood culture with growth in patients followed up in our Internal Intensive Care Unit.

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Detailed Description

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Conditions

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Sepsis Septic Bacteremia and Sepsis Intensive Care Medicine Procalcitonin

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Positive blood culture during their follow up
* Patients over 18 years of age

Exclusion Criteria

* Those under the age of 18
* Those who have had surgery or trauma in the last 72 hours
* Those with a history of autoimmune disease, chronic renal failure
* Patients admitted to intensive care due to acute pancreatitis, pregnancy, burns.
* Patients with incomplete data.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No