Differences in Pain Processing Between Men and Women

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-01

Study Completion Date

2022-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Many chronic pain conditions show clear differences between between men and women, such as reported pain intensities or treatment effects, with chronic pain conditions being generally more frequent in women. Yet, the underlying mechanisms causing these differences are poorly understood. Central sensitization (CS) is considered one important mechanism in pain patients which differs between female and male patients. The central hypothesis is that already in the healthy population CS processes are more pronounced in women than in men.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Association Between Heat Pain Detection Threshold and Area of Secondary Hyperalgesia

NCT02527395

Healthy

COMPLETED NA

Effect of Spinal Cord Stimulation on Pain Thresholds and Sensory Perception in Chronic Pain Patients.

NCT01137617

Chronic Pain

COMPLETED

Neural and Psychological Mechanisms of Pain Perception

NCT02446262

Pain Normal Physiology Healthy Volunteers

RECRUITING NA

Clinical and Scientific Assessment of Pain and Painful Disorders

NCT02707029

Normal Physiology Pain

RECRUITING

Central Sensitisation in Nociceptive and Neuropathic Pain

NCT07321080

Chronic Pain Nociceptive Pain Neuropathic Pain +1 more

ACTIVE_NOT_RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Central Sensitisation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Experimental Arm

Group Type EXPERIMENTAL

Cutaneous thermal stimuli

Intervention Type OTHER

Application of thermal stimuli of different intensities to the skin

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cutaneous thermal stimuli

Application of thermal stimuli of different intensities to the skin

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* good general health
* able to give informed consent

Exclusion Criteria

* pain complaints for more than two consecutive days over the past three months
* any major medical or psychiatric condition (e.g. heart disease, major depressive disorder)
* any chronic pain condition
* inability to follow study instructions
* consumption of stimulants, drugs, or analgesics within the past 24 hours
* scar tissue or generally reduced sensitivity in the designated testing site areas

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes