Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain?

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-03-01

Study Completion Date

2026-06-30

Brief Summary

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The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds and other pain - related variables such as pain tolerance, pain intensity and pain - related negative affect in individuals with chronic pain.

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Detailed Description

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Participants with chronic pain will be randomized into 4 different groups watching different short video-clips (2.20 min), while at the same time experience short-lasting, experimentally induced pain. The negative emotions group will watch an uncomfortable short video containing violence and blood, the positive emotions group will watch a video containing a stand-up comedy show, the neutral emotions group will watch a video about how to paint a house, and the control group will just wait for 2.20 min, without any instructions about what to think about. Pressure pain thresholds, pain tolerance, pain intensity and pain-related negative affect will be measured with an algometer before and after the video-clip combined with experimental pain interventions.

Conditions

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Pain Thresholds Pain Intensity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Within-subjects design

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Experimental: Negative emotion, positive emotion, neutral emotion, control with experimental pain

Arm Description: The intervention includes either a negatively emotionally valenced video, a positively emotionally valenced video, a neutrally emotionally valenced video and experimental pain from the cold pressor test that are simultaneosly applied.

Group Type EXPERIMENTAL

Emotional intervention

Intervention Type OTHER

Emotional intervention Description: The participant will watch a short video-clip with negative emotional content while simultaneously experience experimentally induced pain.

Emotional intervention

Intervention Type OTHER

Description: The participant will watch a short video-clip with positive emotional content while simultaneously experience experimentally induced pain.

Emotional intervention

Intervention Type OTHER

Description: The participant will watch a short video-clip with neutral emotional content while simultaneously experience experimentally induced pain.

Interventions

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Emotional intervention

Emotional intervention Description: The participant will watch a short video-clip with negative emotional content while simultaneously experience experimentally induced pain.

Intervention Type OTHER

Emotional intervention

Description: The participant will watch a short video-clip with positive emotional content while simultaneously experience experimentally induced pain.

Intervention Type OTHER

Emotional intervention

Description: The participant will watch a short video-clip with neutral emotional content while simultaneously experience experimentally induced pain.

Intervention Type OTHER