Prospective Cohort Study of Patients With Infective Endocarditis at Pitié-Salpêtrière Hospital

NCT ID: NCT04992923

Last Updated: 2025-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-15

Study Completion Date

2041-03-31

Brief Summary

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Infective endocarditis (IE) is a severe condition associated with high mortality. Due to the relative low prevalence of IE, prospective data are lacking and current guidelines are mostly based on expert consensus with low level of evidence. IE is also associated with severe complications especially strokes that occur in about one third of the patients.

In order to improve the management and the prognosis of IE, clinical data from larges prospective cohort studies are needed.

Detailed Description

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The study will take place at the Cardiology institute of the Pitié-Salpêtrière hospital. All patients referred to this tertiary care center for IE management will be included.

The characteristics of the patients (demographics, clinical, laboratory, and imaging data) at the time of IE diagnosis and during the follow-up will be collected. The patients will be followed up to 10 years after inclusion.

Conditions

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Infective Endocarditis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients with confirmed IE according to European Society of Cardiology criteria

Exclusion Criteria

* Opposition of the patient to participate
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nadjib Hammoudi, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Pitié-Salpêtrière Hospital (AP-HP)

Locations

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APHP Pitié-Salpêtrière Hospital, Department of Cardiology

Paris, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Nadjib Hammoudi, MD, PhD

Role: CONTACT

+33 142165535

Facility Contacts

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Nadjib Hammoudi, MD, PhD

Role: primary

+33 142165535

Other Identifiers

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APHP200685

Identifier Type: -

Identifier Source: org_study_id

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