Tissue Oxygen Saturation for Esophagectomy

NCT ID: NCT04973046

Last Updated: 2021-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

18 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-01

Study Completion Date

2021-04-30

Brief Summary

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Tissue oxygen saturation monitoring was a useful indicator of blood flow insufficiency in the gastric tube leading to anastomotic leakage during radical esophagectomy.

Detailed Description

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One cause of anastomotic leakage after radical esophagectomy is blood flow insufficiency at the cervical anastomosis site. .

Eighteen patients, who underwent radical esophagectomy with gastric tube reconstruction, were studied. The regional tissue oxygen saturation (rSO2) was measured at the tip (point pre 0) and 2, 4, and 6 cm on the anal side of the tip (point pre 1, pre 2, and pre 3, respectively) before the gastric tube was raised to the cervical site through the retrosternal route. After that, rSO2 was measured at the tip, 2 and 4 cm on the anal side of the tip (points post 0, post 1, and post 2), the actual anastomotic site (point AN), and the chest skin as an indicator of whole-body oxygenation . The relationship between rSO2 scores and the rate of anastomotic leakage was determined.

Conditions

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Esophageal Neoplasms Esophagostomy Complication Anastomotic Leak Oxygen Deficiency

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients who underwent esophagectomy with gastric tube reconstruction from November 2020 to March 2021.

Exclusion Criteria

* Patients who underwent esophagectomy with jejunum or colon reconstruction. patients who underwent two-stage operation.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shizuoka Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Kenjiro Ishii

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shizuoka cancer center

Nagaizumicho, Suntogun, Japan

Site Status

Countries

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Japan

Other Identifiers

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ShizuokaCC rSO2

Identifier Type: -

Identifier Source: org_study_id

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