The Effect of Erythromycin on Occurrence of Leaks From Cervical Esophageal-Gastric Anastomosis After Trans-Hiatal Esophagectomy
NCT ID: NCT00373919
Last Updated: 2007-03-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
INTERVENTIONAL
Brief Summary
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Hypothesis: An early post operative administration of a pro-kinetic dosage of erythromycin will reduce leak occurrence.
Design: This is a prospective, randomized, double blind, placebo controlled study.
Number of patients: 30.
Inclusion Criteria:
* Patients after trans-hiatal esophagectomy
Exclusion Criteria:
* Allergy to erythromycin
* Use of phenothiazine
* QT prolongation
* Liver function test (LFT) abnormalities
* Myasthenia gravis
* Cardiomyopathy
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DOUBLE
Interventions
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intravenous (IV) administration of erythromycin
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Use of phenothiazine
* QT prolongation
* Liver function test (LFT) abnormalities
* Myasthenia gravis
* Cardiomyopathy
18 Years
ALL
No
Sponsors
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Kaplan Medical Center
OTHER
Principal Investigators
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Koram Klein, MD
Role: PRINCIPAL_INVESTIGATOR
Kaplan Medical Center
Central Contacts
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Other Identifiers
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erythro-esophagus
Identifier Type: -
Identifier Source: org_study_id
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