Preoperative Arterial Embolization Before Oncologic Esophagectomy as a Technique for Ischemic Gastric Conditioning

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-30

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This retrospective monocentric comparative study aims to assess the efficacy of preoperative ischemic conditioning, in preventing anastomotic leakage in esophageal cancer surgery. Two groups were included : a surgery-alone group (control group) and a PreopAE group (study group) treated with an embolization procedure before esophagectomy. Collected data included patient characteristics, embolization procedure details, surgical outcomes, and postoperative complications.

The primary outcome was the efficacy of preoperative ischemic conditioning in preventing anastomotic leakage, assessed through CT scans. Secondary outcomes included analyzing safety of ischemic gastric conditioning, hypertrophy of the gastroepiploic artery in embolized patients and comparing hospital stay length and postoperative mortality.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Ischemic Conditioning of the Gastric Conduit in Esophageal Cancer.

NCT04268654

Esophageal Anastomotic Leak Tissue Pressure of Oxygen

COMPLETED NA

Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer

NCT06097078

Esophageal Cancer Esophagus Cancer Anastomotic Leak

RECRUITING

Incidence of Venous Thromboembolism in Patients Undergoing Major Esophageal Resection

NCT03115541

Venous Thromboembolism Thoracic Surgery Esophageal Cancer

COMPLETED

Preemptive Endoluminal Negative Pressure in Minimally Invasive Transthoracic Esophagectomy

NCT04162860

Esophageal Cancer Surgery--Complications Leak, Anastomotic

UNKNOWN NA

Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation

NCT06348381

Esophageal Neoplasm Anastomotic Leak Recurrent Laryngeal Nerve Injuries +2 more

RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Esophageal Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control group

Esophagectomy alone

Collecting data from the medical record

Intervention Type OTHER

Collecting data from the medical record:

* Gastroepiploic artery diameter before and after ischaemic preconditioning
* Postoperative mortality
* Complications related to embolisation and surgery
* Length of stay in intensive care unit and total length of hospital stay

Study Group

Preoperative ischemic conditioning before esophagectomy

Collecting data from the medical record

Intervention Type OTHER

Collecting data from the medical record:

* Gastroepiploic artery diameter before and after ischaemic preconditioning
* Postoperative mortality
* Complications related to embolisation and surgery
* Length of stay in intensive care unit and total length of hospital stay

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Collecting data from the medical record

Collecting data from the medical record:

* Gastroepiploic artery diameter before and after ischaemic preconditioning
* Postoperative mortality
* Complications related to embolisation and surgery
* Length of stay in intensive care unit and total length of hospital stay

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* All patients older than 18 years with an indication for surgical esophagectomy with cervical anastomosis using the Lewis Santy technique or three stages approach.