Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods
NCT ID: NCT04962074
Last Updated: 2021-07-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
22 participants
INTERVENTIONAL
2020-01-05
2020-09-20
Brief Summary
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Materials and Methods: In this prospective study, the semen samples of the patients with astheno-teratozoospermia were divided into two groups for preparation with either the microfluidic or density gradient methods. Selected spermatozoa were used to fertilize the mature sibling oocytes. Semen parameters and embryo development on days 3 and 5 were assessed.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Density gradient method
Sperm prepared by density gradient method
Density gradient
Density gradient centrifugation
Microfluidic chip
Sperm prepared by microfluidic chip method
Microfluidic sperm sorting chip
Fertile Ultimate® (Koek Biotechnology, Turkey) microfluidic sperm sorting chips
Interventions
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Microfluidic sperm sorting chip
Fertile Ultimate® (Koek Biotechnology, Turkey) microfluidic sperm sorting chips
Density gradient
Density gradient centrifugation
Eligibility Criteria
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Inclusion Criteria
* Women were aged from 18 to 39
* Women had at least two mature oocytes.
Exclusion Criteria
MALE
No
Sponsors
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Maltepe University
OTHER
Responsible Party
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Locations
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MaltepeU
Istanbul, , Turkey (Türkiye)
Countries
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Other Identifiers
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2019
Identifier Type: -
Identifier Source: org_study_id
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