Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits
NCT ID: NCT04961112
Last Updated: 2025-04-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
124 participants
INTERVENTIONAL
2021-09-06
2025-04-07
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
TRIPLE
Study Groups
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Experimental - Induced Anxiety
Participants will be administered a shock procedure in which they are exposed to safe electrical shock that will be gradually increase from (1) 30 milliseconds to (4) 80 milliseconds to an individual threshold that is uncomfortable but not painful. Participants will be told they may receive additional shocks for poor performance during cognitive assessments.
Participants will be administered cranial electrotherapy stimulation with a frequency of .5 Hz and a current of 100 microamps during 30 minutes of cognitive assessments of task switching, inhibition (stroop), working memory (n-back), and processing speed (simple reaction time).
Cranial Electrotherapy Stimulation
Participants will receive cranial electrotherapy stimulation stimulation on one of two separate visits (within-subjects).
Experimental - No Induced Anxiety
Participants will be administered a shock procedure in which they are exposed to safe electrical shock that will be gradually increase from (1) 30 milliseconds to (4) 80 milliseconds to an individual threshold that is uncomfortable but not painful. After this procedure, the shock belt will be turned off. Participants will be told they will not receive additional shocks during cognitive assessments.
Participants will be administered cranial electrotherapy stimulation with a frequency of .5 Hz and a current of 100 microamps during 30 minutes of cognitive assessments of task switching, inhibition (stroop), working memory (n-back), and processing speed (simple reaction time).
Cranial Electrotherapy Stimulation
Participants will receive cranial electrotherapy stimulation stimulation on one of two separate visits (within-subjects).
Sham - Induced Anxiety
Participants will be administered a shock procedure in which they are exposed to safe electrical shock that will be gradually increase from (1) 30 milliseconds to (4) 80 milliseconds to an individual threshold that is uncomfortable but not painful. Participants will be told they may receive additional shocks for poor performance during cognitive assessments.
Participants will be administered sham cranial electrotherapy stimulation with no current during 30 minutes of cognitive assessments of task switching, inhibition (stroop), working memory (n-back), and processing speed (simple reaction time).
Sham Cranial Electrotherapy Stimulation
Participants will receive sham stimulation on one of two separate visits (within-subjects).
Sham - No Induced Anxiety
Participants will be administered a shock procedure in which they are exposed to safe electrical shock that will be gradually increase from (1) 30 milliseconds to (4) 80 milliseconds to an individual threshold that is uncomfortable but not painful. After this procedure, the shock belt will be turned off. Participants will be told they will not receive additional shocks during cognitive assessments.
Participants will be administered sham cranial electrotherapy stimulation with no current during 30 minutes of cognitive assessments of task switching, inhibition (stroop), working memory (n-back), and processing speed (simple reaction time).
Sham Cranial Electrotherapy Stimulation
Participants will receive sham stimulation on one of two separate visits (within-subjects).
Interventions
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Cranial Electrotherapy Stimulation
Participants will receive cranial electrotherapy stimulation stimulation on one of two separate visits (within-subjects).
Sham Cranial Electrotherapy Stimulation
Participants will receive sham stimulation on one of two separate visits (within-subjects).
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
28 Years
ALL
Yes
Sponsors
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Tufts University
OTHER
Responsible Party
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Nathan Ward
Associate Professor
Locations
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Tufts University
Medford, Massachusetts, United States
Countries
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Other Identifiers
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1908026
Identifier Type: -
Identifier Source: org_study_id
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