The Role of Deep Cerebral Vein Variation in Patients With Angiographic Negative Subarachnoid Hemorrhage

NCT ID: NCT04941846

Last Updated: 2021-06-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

296 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-31

Study Completion Date

2023-01-31

Brief Summary

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The incidence of Rosenthal basilar vein (BVR) variants (deep venous drainage variants) was relatively increased in patients with AN-SAH compared with patients with aneurysms. However, the inclusion criteria for AN-SAH patients in these studies were different. Some studies have investigated both PAN-SAH and NPAN-SAH, while some studies have only investigated PAN-SAH patients. However, we believe that NPAN-SAH may be the bleeding caused by non-BVR variation. Although previous studies did not find any association between NPAN-SAH and BVR variants, the results in their study were different, which may be due to the limited number of cases.

Detailed Description

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Conditions

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Subarachnoid Hemorrhage, Aneurysmal

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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nimodipine and euvolemia

administered nimodipine to prevent vasospasm, and euvolemia was maintained via intravenous hydration

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Patients with negative subarachnoid hemorrhage diagnosed by DSA

Exclusion Criteria

1. In patients with aneurysms, external ventricular drainage (EVD) alone or decompression craniotomy alone or conservative treatment was performed
2. Have a history of trauma or prior brain injury (stroke, cerebral hemorrhage, etc., with associated chronic changes on CT)
3. Patients with loss of imaging data and severe comorditions prior to onset of SAH
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yuanjian Fang, MD

Role: PRINCIPAL_INVESTIGATOR

2ndAffiliated Hospital, School of Medicine, Zhejiang University, China

Locations

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2ndAffiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Jianmin Zhang, MD

Role: CONTACT

+86 13805722695

Sheng Chen, MD

Role: CONTACT

+86 13645814323

Facility Contacts

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Jianmin Zhang, MD

Role: primary

+86 13805722695

Sheng Chen, MD

Role: backup

+86 13645814323

Other Identifiers

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2020111

Identifier Type: -

Identifier Source: org_study_id

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