Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA

NCT ID: NCT04913935

Last Updated: 2021-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-05

Study Completion Date

2020-01-15

Brief Summary

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In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters, radial subluxation rate, functional level and hand dexterity.

Detailed Description

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Patients diagnosed with trapeziometacarpal osteoarthritis and healthy subjects will be included in the study. Thickness and cross-sectional area measurements of the thenar muscles of the patient and healthy volunteers will be performed by using Shimadzu SDU 1200-Pro ultrasound system with an 8-10 MHz linear probe. To improve the image quality and to avoid muscle compression, water immersion ultrasonography will be preferred and the hands will be positioned in a water-filled plastic container. The thenar muscles will be imaged in hands of each subject.

In this study, poster-anterior radiographic imaging will be performed. The osteoarthritis stage will be determined on the radiographic image. Three different measurements will be performed on radiography: radial subluxation of the first metacarpal base (RS), articular width (AW) of the first metacarpal, and the distance between the ulnar articular facet of the trapezium and the ulnar edge of the metacarpal (U). RS / AW ratio will be calculated.

Because TMC OA caused pain and affect performance, especially during grip activities in the osteoarthritis and control groups will be tested.

Grip strength will also be measured.

Conditions

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Thumb Osteoarthritis Muscle Atrophy or Weakness

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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TMC OA

women who were diagnosed with TMC OA

Muscle-Skeleton Ultrasonography

Intervention Type DIAGNOSTIC_TEST

postero-anterior radiography

Control

healty volunteer women

Muscle-Skeleton Ultrasonography

Intervention Type DIAGNOSTIC_TEST

postero-anterior radiography

Interventions

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Muscle-Skeleton Ultrasonography

postero-anterior radiography

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Radiography

Eligibility Criteria

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Inclusion Criteria

* Patients with trapeziometacarpal osteoarthritis who were between 35 and 75 years

Exclusion Criteria

* Patient with De'quervain tenosynovitis, trigger finger, entrapment neuropathy and who had undergone hand surgery were excluded.
Minimum Eligible Age

35 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

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Feray Karademir

Research Asssistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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ÇİĞDEM AYHAN, ASS. PROF.

Role: STUDY_CHAIR

Hacettepe University

Locations

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Hacettepe University

Altindağ, Ankara, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Wolf JM, Oren TW, Ferguson B, Williams A, Petersen B. The carpometacarpal stress view radiograph in the evaluation of trapeziometacarpal joint laxity. J Hand Surg Am. 2009 Oct;34(8):1402-6. doi: 10.1016/j.jhsa.2009.06.030. Epub 2009 Sep 10.

Reference Type BACKGROUND
PMID: 19744803 (View on PubMed)

Mohseny B, Nijhuis TH, Hundepool CA, Janssen WG, Selles RW, Coert JH. Ultrasonographic quantification of intrinsic hand muscle cross-sectional area; reliability and validity for predicting muscle strength. Arch Phys Med Rehabil. 2015 May;96(5):845-53. doi: 10.1016/j.apmr.2014.11.014. Epub 2014 Dec 4.

Reference Type BACKGROUND
PMID: 25482051 (View on PubMed)

Grechenig W, Peicha G, Weiglein A, Tesch P, Lawrence K, Mayr J, Preidler KW. Sonographic evaluation of the thenar compartment musculature. J Ultrasound Med. 2000 Nov;19(11):733-41. doi: 10.7863/jum.2000.19.11.733.

Reference Type BACKGROUND
PMID: 11065261 (View on PubMed)

Other Identifiers

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GO 18/204

Identifier Type: -

Identifier Source: org_study_id

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